Restenosis Clinical Trial
Official title:
Search for Restenosis Markers in Lower Limb Arteritis
The initial hypothesis of this work is that the genesis and the evolution of the atheromatous
plaque are partly controlled at the molecular level and in particular by the microRNAs
through their role as regulator of the genes.
The study of the tissue and serum profile over time of specific microRNAs involved in the
regulation of atheromatous plaque correlated with clinical data and restenosis imaging will
allow to define biological markers of restenosis in the patient with an arteritis of the
lower limbs .
This study is a pioneer in the field and it would be imprudent to conclude that a biomarker
would be used clinically at the end of this work alone. Nevertheless this study will make a
major advance in this topic, in vivo intervention studies with inhibition or over-expression
of microRNA will obviously be necessary to confirm the use of these as biomarkers of
arteritis of the lower limbs.
Regular assay of reliable biomarkers in arterial patients will ultimately suggest early
management to best adapt surgical and medical treatment.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT01970579 -
Clinical Trial on Peripheral Arteries Treated With SeQuent® Please P Paclitaxel Coated Balloon Catheter
|
Phase 3 | |
| Completed |
NCT01861860 -
OPtimized Stenting Using Intravascular Ultrasound(IVUS) in Long lEsion: Rationale for Simplified criteriA
|
N/A | |
| Completed |
NCT01722877 -
JetStream (JS) Atherectomy in Femoropopliteal In-Stent Restenotic Lesions
|
N/A | |
| Recruiting |
NCT00774917 -
Numen Stent Assessment Using OCT Technique in a Single Center Study
|
Phase 2/Phase 3 | |
| Completed |
NCT00647504 -
Prospective Clinical Observational Registry Including Consecutive Patients With In-stent Restenosis or Stent Thrombosis
|
N/A | |
| Completed |
NCT00493597 -
Blood Endothelium Progenitor Cells and Dendritic Cells as Predictive Biomarkers of In-stent Restenosis
|
||
| Not yet recruiting |
NCT01476020 -
Is There A LIfe for Drug Eluting Stent (DES) After Discontinuation of Clopidogrel
|
Phase 3 | |
| Terminated |
NCT00780156 -
The ITALIC Study: Is There A LIfe for Drug-eluting Stents (DES) After Discontinuation of Clopidogrel
|
N/A | |
| Terminated |
NCT00712257 -
Study to Evaluate the Safety and Performance of Spectranetics Laser w/Adjunct PTA and Gore Viabahn Endoprosthesis for Treatment of SFA Instent Restenosis
|
N/A | |
| Completed |
NCT01065532 -
SEDUCE OCT Study in Coronary Artery rEstenosis:an Optical Coherence Tomography (OCT) Study
|
N/A | |
| Recruiting |
NCT03613337 -
Effect of Smoking Status and Genetic Risk Factors on Restenosis and Efficacy of Clopidogrel After de Novo Percutaneous Coronary Intervention
|
||
| Completed |
NCT03332264 -
Sequent Please Drug Coated Balloons Versus Primary Stent Application in Long SFA Lesions
|
N/A | |
| Completed |
NCT02063672 -
Lutonix® Drug Coated Balloon vs. Standard Balloon Angioplasty for Treatment of Femoropopliteal In-Stent Restenosis
|
N/A | |
| Recruiting |
NCT05451368 -
Neointimal Features in Patients With Restenosis of Calcified Lesions
|
||
| Completed |
NCT02649946 -
Clinical Study of the BARD® COVERA™ Arteriovenous (AV) Stent Graft
|
N/A | |
| Completed |
NCT01632371 -
Intracoronary Stenting and Angiographic Results: Optimizing Treatment of Drug Eluting Stent In-Stent Restenosis 4
|
Phase 4 | |
| Completed |
NCT00798954 -
Treatment of Bifurcation Lesions by SINGLE STENT and KISSing Balloon Trial
|
Phase 4 | |
| Completed |
NCT02790606 -
Clinical Study of the BARD® COVERA™ Arteriovenous (AV) Stent Graft in AV Graft Patients (AVeVA)
|
N/A | |
| Completed |
NCT01405248 -
Butylphthalide for Preventing Restenosis After Intracranial and Extracranial Artery Stenting
|
Phase 3 | |
| Completed |
NCT00987324 -
Efficacy Study of Paclitaxel-eluting Balloon, -Stent vs. Plain Angioplasty for Drug-eluting Stent Restenosis
|
Phase 4 |