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Response to Hyperoxia clinical trials

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NCT ID: NCT02267031 Completed - Hypocapnia Clinical Trials

The Role of Perioperative Ventilation (Gas Exchange) During Intrabdominal Surgery on Cognitive Function

ACDYS
Start date: October 2012
Phase: N/A
Study type: Interventional

Abdominal surgery commonly requires perioperative relaxation and therefore controlled mechanical ventilation. However, respiratory support can be associated with minor, yet clinically significant changes in blood gas content. The inadvertent hyperoxia (excessively high oxygen) and/or hypocapnia (excessively low carbon dioxide) can result in transient changes in cerebral blood flow and cognitive impair.

NCT ID: NCT01793454 Completed - Clinical trials for Response to Hyperoxia

Hyperoxic Oxidative Stress During Abdominal Surgery

Start date: February 2013
Phase: N/A
Study type: Interventional

Our aim is to compare the effects of 80% and 40% Fraction of inspired oxygen on oxidative stress, antioxidant response (in plasma and bronchoalveolar lavage), extubation quality, preanesthetic and postanesthetic expiration tidal volumes.

NCT ID: NCT01690650 Completed - Clinical trials for Response to Hyperoxia

Neonatal Cerebral Oxygenation After Exposure to Oxygen Evaluated With the INVOS Oximeter

Start date: September 2012
Phase: N/A
Study type: Interventional

- Due to the increased risk of brain damage, continuous monitoring of the cerebral oxygenation is interesting. The investigators will evaluate the capability of the INVOS Oximeter to detect induced changes in the cerebral regional saturation. - The purpose of the study is to investigate our hypothesis that cerebral vasoconstriction after oxygen exposure is prolonged in preterm infants compared to term infants.