Respiratory Viral Infection Clinical Trial
Official title:
A Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Trial of ZX-7101A Tablets to Evaluate the Efficacy and Safety in the Treatment of Uncomplicated Influenza in Adolescents
The primary object of this study is evaluating the efficacy of ZX-7101A tablets versus placebo in the treatment of uncomplicated simple influenza in adolescents. The seongdary object is evaluating the safety of ZX-7101A tablet in the treatment of uncomplicated simple influenza in adolescents.
In this study, adolescents aged 12 and < 18 with uncomplicated influenza are selected as subjects. Typical systemic and/or respiratory influenza symptoms were required, and the time interval between the first onset of influenza symptoms and random enrollment was less than 48 hours. This study is divided into screening/treatment period (D1) and observation period (about 2 weeks). You will be eligible before starting study therapy on day 1 (D1). Participants were randomly assigned 1:1 to ZX-7101A group (dose 40 mg, administration once) or placebo group (dose 1 placebo tablet, administration once), with 180 participants planned to be included in each group, for a total of about 360 participants. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Terminated |
NCT04898023 -
Zinc and Green Tea Extract for Community Respiratory Viral Infections
|
Phase 2 | |
| Withdrawn |
NCT04842331 -
PREvent Viral Exposure and Transmission Study: a COVID-19 (SARS-CoV-2) PEP Study (PREVENT)
|
Phase 2/Phase 3 | |
| Completed |
NCT02260596 -
Respiratory Viral Infections in Pediatric Transplantation
|
N/A | |
| Completed |
NCT04898140 -
The Evaluation of Cellular and Humoral Immunity to COVID-19 in Moscow Residents
|
||
| Completed |
NCT04611061 -
Kagocel® for the Prevention of ARVI and Influenza in Adults Health Care Workers
|
||
| Not yet recruiting |
NCT05618483 -
Xylitol Based Nasal Spray for COVID-19 Treatment
|
N/A | |
| Recruiting |
NCT06149494 -
RCT of Vapendavir in Patients With COPD and Human Rhinovirus/Enterovirus Upper Respiratory Infection
|
Phase 2 | |
| Terminated |
NCT04141917 -
Test-and-treat for Influenza in Homeless Shelters
|
Phase 4 | |
| Recruiting |
NCT06017310 -
Respiferon Project
|
||
| Enrolling by invitation |
NCT06188988 -
Viral Infections and Airway Microbiome in Young Children With Cystic Fibrosis
|
||
| Completed |
NCT04141930 -
Pilot of Cohort of Households for Influenza Monitoring and Evaluation in Seattle
|
Phase 4 | |
| Completed |
NCT05846360 -
The Technical and Operational Performance of the QuidelOrtho Savanna RVP4 Analyzer
|
||
| Completed |
NCT04532411 -
COVID-19 Testing Sample Acquisition Throughput and Efficiency
|
||
| Active, not recruiting |
NCT04258059 -
Wells and Enteric Disease Transmission Trial (WET - Trial)
|
N/A | |
| Active, not recruiting |
NCT04482673 -
Vitamin D Supplementation in the Prevention and Mitigation of COVID-19 Infection
|
Phase 4 | |
| Not yet recruiting |
NCT05946538 -
Clinical Evaluation of SARS-COV-2 (COVID-19), Influenza and RSV 8-Well MT-PCR Panel for In Vitro Diagnostics
|
N/A | |
| Recruiting |
NCT05092607 -
Evaluation of the Detection Performance of the N Antigenemia of SARS-CoV-2 in the General Population for the Diagnosis and Screening of COVID-19
|
N/A | |
| Recruiting |
NCT05913700 -
Effect of Respiratory Virus Infection on EmeRgencY Admission Study (EVERY Study)
|
||
| Recruiting |
NCT04826991 -
Wells and Enteric Disease Transmission
|
N/A | |
| Terminated |
NCT04664075 -
Predicting Severity and Disease Progression in Influenza-like Illness (Including COVID-19)
|