Respiratory Viral Infection Clinical Trial
Official title:
Evaluation of the Type 1 IFN Response in Viral Infections
Respiratory viral infections (RVIs) represent a major public health problem and a great burden in terms of morbidity and mortality in children and adults worldwide. To ascertain the source of an infection, microbiology laboratories routinely perform a crucial step: the search for the pathogen through Polymerase Chain Reaction (PCR). Due to the extensive variety of pathogens, testing for the existence of all potential viruses, bacteria, or fungi accountable for the infection is an impractical and time-intensive endeavor. Furthermore, the rise of novel pathogens, exemplified by those accountable for the recent SARS-CoV-2 pandemic, underscores the urgency of promptly developing new innovative diagnostic tests. To address these needs, researchers have dedicated several years to developing indirect methodologies notably centered around utilizing markers derived from the host's immune system. Among these, one particularly promising approach focuses on measuring the expression of interferon-stimulated genes, which are uniquely triggered by viral infections, thereby facilitating viral diagnosis. This methodology's efficacy has been proven in the context of SARS-CoV-2 infections. This study's objective is to assess the functionality of such a tool across a spectrum of Respiratory Viral Infections (RVIs) prevalent within a French population during the winter season.
n/a
Status | Clinical Trial | Phase | |
---|---|---|---|
Terminated |
NCT04898023 -
Zinc and Green Tea Extract for Community Respiratory Viral Infections
|
Phase 2 | |
Withdrawn |
NCT04842331 -
PREvent Viral Exposure and Transmission Study: a COVID-19 (SARS-CoV-2) PEP Study (PREVENT)
|
Phase 2/Phase 3 | |
Completed |
NCT02260596 -
Respiratory Viral Infections in Pediatric Transplantation
|
N/A | |
Not yet recruiting |
NCT06099873 -
A Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Trial of ZX-7101A Tablets to Evaluate the Efficacy and Safety in the Treatment of Uncomplicated Influenza in Adolescents
|
Phase 3 | |
Completed |
NCT04898140 -
The Evaluation of Cellular and Humoral Immunity to COVID-19 in Moscow Residents
|
||
Completed |
NCT04611061 -
Kagocel® for the Prevention of ARVI and Influenza in Adults Health Care Workers
|
||
Not yet recruiting |
NCT05618483 -
Xylitol Based Nasal Spray for COVID-19 Treatment
|
N/A | |
Recruiting |
NCT06149494 -
RCT of Vapendavir in Patients With COPD and Human Rhinovirus/Enterovirus Upper Respiratory Infection
|
Phase 2 | |
Terminated |
NCT04141917 -
Test-and-treat for Influenza in Homeless Shelters
|
Phase 4 | |
Enrolling by invitation |
NCT06188988 -
Viral Infections and Airway Microbiome in Young Children With Cystic Fibrosis
|
||
Completed |
NCT04141930 -
Pilot of Cohort of Households for Influenza Monitoring and Evaluation in Seattle
|
Phase 4 | |
Completed |
NCT05846360 -
The Technical and Operational Performance of the QuidelOrtho Savanna RVP4 Analyzer
|
||
Completed |
NCT04532411 -
COVID-19 Testing Sample Acquisition Throughput and Efficiency
|
||
Active, not recruiting |
NCT04258059 -
Wells and Enteric Disease Transmission Trial (WET - Trial)
|
N/A | |
Active, not recruiting |
NCT04482673 -
Vitamin D Supplementation in the Prevention and Mitigation of COVID-19 Infection
|
Phase 4 | |
Not yet recruiting |
NCT05946538 -
Clinical Evaluation of SARS-COV-2 (COVID-19), Influenza and RSV 8-Well MT-PCR Panel for In Vitro Diagnostics
|
N/A | |
Recruiting |
NCT05092607 -
Evaluation of the Detection Performance of the N Antigenemia of SARS-CoV-2 in the General Population for the Diagnosis and Screening of COVID-19
|
N/A | |
Recruiting |
NCT05913700 -
Effect of Respiratory Virus Infection on EmeRgencY Admission Study (EVERY Study)
|
||
Recruiting |
NCT04826991 -
Wells and Enteric Disease Transmission
|
N/A | |
Terminated |
NCT04664075 -
Predicting Severity and Disease Progression in Influenza-like Illness (Including COVID-19)
|