Work-related Respiratory Symptoms in Champagne Vineyard Workers

Respiratory Symptoms Clinical Trial

— VIN-ALLERGO  

Official title:

Work-related Respiratory Symptoms in Champagne Vineyard Workers

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02883920
• Other study ID #: 2015Ao004
• Status: Completed
• Phase: N/A
• First received: August 25, 2016
• Last updated: August 29, 2016
• Start date: January 2007
• Est. completion date: January 2012

Study information

• Verified date: August 2016
• Source: CHU de Reims
• Contact: n/a
• Is FDA regulated: No
• Health authority: France: Commission nationale de l'informatique et des libertés
• Study type: Observational

Clinical Trial Summary

Work related asthma and rhinitis are frequent diseases with a significant morbidity and a social and economic impact. Farmers are highly exposed to various inhaled agents such as organic or inorganic dust, endotoxin, micro-organisms, pollen, mites, moulds, animal danders and pesticides, inducing rhinitis, asthma, chronic bronchitis, hypersensitivity pneumonitis and organic dust toxic syndrome. Work related respiratory symptoms are frequent in crop farmers. Allergic rhinitis and respiratory symptoms in fruit farmers are mainly related to pollen allergy, especially gramineae pollen. They can also be related to the use of pesticides or exposure to mites .

Description:

Aim of the study were :

to determine the prevalence of work related respiratory symptoms in workers of Champagne vineyard in France to analyze the relationships between respiratory symptoms, occupational exposure and sensitization profile in workers of Champagne vineyard in France

Recruitment information / eligibility

• Status: Completed
• Enrollment: 307
• Est. completion date: January 2012
• Est. primary completion date: December 2010
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• workers of Champagne vineyard

• aged > 18 years

Study Design

Observational Model: Case-Only, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

• Respiratory Symptoms
• Signs and Symptoms, Respiratory

Intervention

Other:
• Allergy and respiratory functional tests

Locations

Country	Name	City	State
France	Chu de Reims	Reims

Sponsors (1)

Lead Sponsor	Collaborator
CHU de Reims

Country where clinical trial is conducted

France, 

References & Publications (1)

Perotin JM, Barbe C, Nguyen KL, Fontaine JF, Gabignon Y, Nardi J, Launois C, Lebargy F, Lavaud F, Deslee G. Work-related respiratory symptoms in Champagne vineyard workers. Eur Ann Allergy Clin Immunol. 2015 Sep;47(5):140-4. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Sensitization	A positive skin prick test was defined as the presence of a mean wheal diameter of 3 mm or more than the negative control. Sensitization was defined by a positive skin reaction to one or more allergens	Day 0	No