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Respiratory Sounds clinical trials

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NCT ID: NCT05839756 Recruiting - Stridor Clinical Trials

Predicting Post Extubation Stridor After Maxillomandibular Fixation

airway
Start date: May 3, 2023
Phase: N/A
Study type: Interventional

Endotracheal intubation can induce laryngotracheal injury which results in narrowing of the airway due to edema of the glottis. This can increase the risk of development of post-extubation stridor (PES)

NCT ID: NCT05812378 Recruiting - Respiratory Rate Clinical Trials

Respiratory Monitoring System Safety and Performance Study

Start date: March 24, 2023
Phase:
Study type: Observational

The goal of this observational study is collect data to evaluate the efficacy of the RMS system in monitoring, recording, and presenting respiratory function data to the user in participants scheduled for pulmonary function testing (PFT). Participants will complete: - 60 episodes of data collection with a decreased tidal volume - 30 episodes of data collection with an increased tidal volume - 80 episodes with normal tidal volume breathing The TSS will continuously transmit sound data to an adjacent personal computer (PC) via Bluetooth Low-Energy (BLE). TSS trachea sound data will be recorded on the PC and then transmitted via a secure wireless network to an RTM cloud account that is HIPPA compliant. Reference breathing data will be simultaneously recorded using an FDA approved hospital ventilator (Hamilton Medical, HAMILTON-C1) with a calibrated pneumotach, capnometer, and a tight-fitting face mask. This system accurately measures and records a spontaneously breathing patient's RR, TV, MV, and end-tidal carbon dioxide concentration.

NCT ID: NCT05710081 Recruiting - Asthma in Children Clinical Trials

Bacterial Lysate In Preventing Asthma

BLIPA
Start date: November 30, 2021
Phase: Phase 3
Study type: Interventional

The goal of this clinical trial is to learn about the effects of using bacterial lysate in bronchiolitis. The main question it aims to answer are: Does the use of bacterial lysate after bronchiolitis reduce the likelihood of preschool wheeze Participants will take either the active medicine or a placebo for 24 months.

NCT ID: NCT05684848 Recruiting - Wheezing Clinical Trials

Evaluate the Effect of Nasal Spray in the Prevention of RTI in Children With Pre-school Wheezing

Start date: November 1, 2022
Phase: N/A
Study type: Interventional

To determine whether or not preventive administration of resveratrol in the form of a nasal spray is effective in reducing the number of asthma exacerbations typical of preschool wheezing children who develop viral infections.

NCT ID: NCT05677763 Recruiting - Clinical trials for Respiratory Tract Infections

OM-85 in Paediatric Recurrent Respiratory Tract Infections With Wheezing Lower Respiratory Illness

Start date: December 12, 2022
Phase: Phase 4
Study type: Interventional

This study will assess the efficacy and safety of OM-85 compared to placebo in reducing the number of respiratory tract infections (RTIs) in children aged between 6 months and 5 years.

NCT ID: NCT05667701 Recruiting - Asthma in Children Clinical Trials

Soy Isoflavones For Inner City Infants At Risk For Asthma (SIRA) Study

SIRA
Start date: March 15, 2024
Phase: Phase 2
Study type: Interventional

The goal of this clinical trial is to compare soy isoflavones to placebo in children who at risk of asthma and have a genetic variation which results in them making more of a pro-inflammatory protein, plasminogen activator inhibitor-1. The main questions this trail seeks to answer is: will soy isoflavones decrease wheezing episodes in these children when given in the first year of life. Participants will be asked to ingest soy isoflavone or placebo twice daily mixed into a liquid or puree vehicle for 7 months from randomization. There will be 3 mandatory in-person visits, and 6 virtual visits in the first year. There will also be 11 monthly questionnaires and 1 in person visit in the observation year. Participants will have 4 nasal swabs, 3 blood draws, and also provide 4 stool samples over the course of the study.

NCT ID: NCT05444699 Recruiting - Clinical trials for Bronchiolitis Acute Viral

Oral Prednisolone for Acute Rhinovirus Induced Wheezing in Children Less Than 2 Years of Age

RhinoPOCRCT
Start date: October 11, 2022
Phase: Phase 4
Study type: Interventional

The aim of the trial is to evaluate whether the use of oral prednisolone directed by point-of-care testing is useful in acute wheezing caused by rhinovirus in children aged 6-24 months.

NCT ID: NCT05405127 Recruiting - Low Back Pain Clinical Trials

Breathing and Core Stability Exercise Effects on Lumbopelvic Pain

Start date: May 30, 2022
Phase: N/A
Study type: Interventional

Lumbopelvic pain refers to self-reported pain in areas of lower region, anterior and posterior pelvic tilt or combination of these. Physical therapy interventions used are breathing exercises with and without core stability exercises. Tool used were Pain Pressure Algometer and Oswestry Disability Index.

NCT ID: NCT05250635 Recruiting - Thoracic Surgery Clinical Trials

Analysis of Breath Sound During Thoracic Surgery

Start date: February 2022
Phase:
Study type: Observational [Patient Registry]

In modern thoracic surgery, double-lumen endobronchial tube (DLET) is the first choice for intubation. One lung ventilation can be perfectly performed by DLET, with the benefit of maintaining adequate gas exchange and establishing great surgical field. Traditionally, we use stethoscope and fiberscope for DLET site evaluation. However, there are some concerns over traditional methods. Stethoscope evaluation can be subjective from person to person; fiberscope, on the other hand, can cause additional bronchial injury as it is an invasive procedure. We hope to utilize patches, also known as electronic stethoscope, which provide non-invasive and visualized spectrum information, to assist anesthesiologists evaluate DLET insertion site more precisely in patients undergo thoracic surgery.

NCT ID: NCT05145894 Recruiting - Asthma Clinical Trials

Differentiation of Asthma/COPD Exacerbation and Stable State Using Automated Lung Sound Analysis With LungPass Device

Start date: September 30, 2021
Phase:
Study type: Observational

This observational study evaluates whether lung sound analysis with LungPass device can be used to differentiate exacerbation and stable state asthma and COPD.