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Respiratory Muscle Weakness clinical trials

View clinical trials related to Respiratory Muscle Weakness.

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NCT ID: NCT04947436 Completed - Clinical trials for Amyotrophic Lateral Sclerosis

ALS and Airway Clearance (ALSAC) Therapy

ALSAC
Start date: January 25, 2012
Phase: N/A
Study type: Interventional

Patients will receive one of three respiratory therapy interventions for airway clearance assistance: 1) High frequency chest wall oscillation (HFCWO) and mechanical insufflation/exsufflation (MIE), 2) HFCWO or 3) MIE. The study period will be six months and include three clinic visits, baseline and follow-up visits at 3 and 6 months, and 6 monthly home visits by the respiratory therapist.

NCT ID: NCT02508311 Terminated - Spinal Cord Injury Clinical Trials

Albuterol to Improve Respiratory Strength in SCI

Start date: June 1, 2016
Phase: Phase 4
Study type: Interventional

Spinal cord injury (SCI), especially involving the cervical and upper thoracic segments, can significantly compromise respiratory muscle function. Respiratory complications can ensue, including lung collapse and pneumonia, which are the primary cause for mortality in association with traumatic SCI both during the acute and chronic phases post-injury. Lesions at the level of the cervical or high thoracic spinal cord result in respiratory muscle weakness, which is associated with ineffective cough, mucus retention, and mucus plugging. Despite the fact that pulmonary complications are a major cause of morbidity and mortality in this population, there is a paucity of effective interventions in the SCI population known to improve respiratory muscle strength with pharmacologic interventions receiving little to no attention. The current objective of this study is to determine the effectiveness of 16 weeks of sustained release oral Albuterol to; (1) improve respiratory muscular strength, and (2) improve cough effectiveness.

NCT ID: NCT02469064 Completed - Clinical trials for Respiratory Muscle Weakness

Effects of Respiratory Muscle Training in Mechanically Ventilated Adults

RMTMVA
Start date: September 2014
Phase: N/A
Study type: Interventional

Respiratory muscle training (RMT) is considered a therapeutic strategy to improve respiratory muscle strength in mechanically ventilated (MV) patients and facilitates ventilator weaning. RMT aims at improving strength and endurance of respiratory muscles . However, scarce research exists regarding evaluation of RMT in MV patients and additionally studies differ in methods, RMT protocols and subjects included. There are not reports about Colombian studies evaluating RMT effects on MV patients. The aim of this study is to evaluate the effectiveness of respiratory muscle training in increasing respiratory muscle strength and improving weaning outcomes in MV patients who required ventilatory support for more than 48 hours at an Intensive Care Unit of an IV level Hospital in Cali during the period 2014-2015