Asthma Clinical Trial
Official title:
The Impact of Insulating Domestic Houses on the Health of Occupants: an Intervention Study
In six communities we will seek out households where someone who has a history of respiratory problems. For the first winter we will measure temperature and humidity of the house and health of occupants. We will insulate half the houses and the next winter compare them with the uninsulated houses to see if warmer houses improve health.
Damp, cold indoor environments are bad for the health of people who live in them,
particularly if they have respiratory problems or are vulnerable, such as the young or the
very old. This is a community based study designed to test the hypothesis that insulating
domestic houses will make them warmer and that this increase in indoor temperature will
improve their health and wellbeing.
Following two pilot studies, the first among older people in city council flats and the
second among home owners in Waitara. We have followed the "Waitara model" where community
networks will be mobilised to identify households in each community where there is someone
with a on going respiratory problem. Seven communities have been selected to help test these
hypotheses and have agreed to participate Otara, Gisborne, Mahia/Nuhaka, Taranaki, Porirua,
West Coast and Christchurch. Low income areas with high Maori populations have been
deliberately selected to maximise the potential health gains.
Two hundred houses in each community will be insulated free of charge to the occupants. The
workers who will insulate the homes will be local people employed through the Department of
Work and Income (WINZ).
Once the houesholds are selected they will be randomly assigned to intervention or control
groups. During the first winter, all 1400 households will be monitored for temperature and
humidity and their comfort, health and healthcare utilization will be recorded. Half the
households, assigned to the intervention group, will be fully insulated during the spring.
The following winter, all the initial measurements taken from both the intervention and
control group will be repeated. At the end of the study period, all control houses will be
insulated.
This study has developed from a natural intervention being carried out by the Energy
Efficiency Conservation Authority (EECA) to insulate domestic houses in New Zealand and is a
major collaborative effort, which will shed light on the effectiveness of insulation in
improving health and wellbeing. The impact of housing refurbishment on health has not
previously been examined. There is considerable government and policy interest in promoting
healthy housing and there is strong community interest in ensuring the housing stock is
improved in order to lower health risks.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention
Status | Clinical Trial | Phase | |
---|---|---|---|
Terminated |
NCT04410523 -
Study of Efficacy and Safety of CSJ117 in Patients With Severe Uncontrolled Asthma
|
Phase 2 | |
Completed |
NCT04624425 -
Additional Effects of Segmental Breathing In Asthma
|
N/A | |
Active, not recruiting |
NCT03927820 -
A Pharmacist-Led Intervention to Increase Inhaler Access and Reduce Hospital Readmissions (PILLAR)
|
N/A | |
Completed |
NCT04617015 -
Defining and Treating Depression-related Asthma
|
Early Phase 1 | |
Recruiting |
NCT03694158 -
Investigating Dupilumab's Effect in Asthma by Genotype
|
Phase 4 | |
Terminated |
NCT04946318 -
Study of Safety of CSJ117 in Participants With Moderate to Severe Uncontrolled Asthma
|
Phase 2 | |
Completed |
NCT04450108 -
Vivatmo Pro™ for Fractional Exhaled Nitric Oxide (FeNO) Monitoring in U.S. Asthmatic Patients
|
N/A | |
Completed |
NCT03086460 -
A Dose Ranging Study With CHF 1531 in Subjects With Asthma (FLASH)
|
Phase 2 | |
Completed |
NCT01160224 -
Oral GW766944 (Oral CCR3 Antagonist)
|
Phase 2 | |
Completed |
NCT03186209 -
Efficacy and Safety Study of Benralizumab in Patients With Uncontrolled Asthma on Medium to High Dose Inhaled Corticosteroid Plus LABA (MIRACLE)
|
Phase 3 | |
Completed |
NCT02502734 -
Effect of Inhaled Fluticasone Furoate on Short-term Growth in Paediatric Subjects With Asthma
|
Phase 3 | |
Completed |
NCT01715844 -
L-Citrulline Supplementation Pilot Study for Overweight Late Onset Asthmatics
|
Phase 1 | |
Terminated |
NCT04993443 -
First-In-Human Study to Evaluate the Safety, Tolerability, Immunogenicity, and Pharmacokinetics of LQ036
|
Phase 1 | |
Completed |
NCT02787863 -
Clinical and Immunological Efficiency of Bacterial Vaccines at Adult Patients With Bronchopulmonary Pathology
|
Phase 4 | |
Recruiting |
NCT06033833 -
Long-term Safety and Efficacy Evaluation of Subcutaneous Amlitelimab in Adult Participants With Moderate-to-severe Asthma Who Completed Treatment Period of Previous Amlitelimab Asthma Clinical Study
|
Phase 2 | |
Completed |
NCT03257995 -
Pharmacodynamics, Safety, Tolerability, and Pharmacokinetics of Two Orally Inhaled Indacaterol Salts in Adult Subjects With Asthma.
|
Phase 2 | |
Completed |
NCT02212483 -
Clinical Effectiveness and Economical Impact of Medical Indoor Environment Counselors Visiting Homes of Asthma Patients
|
N/A | |
Recruiting |
NCT04872309 -
MUlti-nuclear MR Imaging Investigation of Respiratory Disease-associated CHanges in Lung Physiology
|
||
Withdrawn |
NCT01468805 -
Childhood Asthma Reduction Study
|
N/A | |
Recruiting |
NCT05145894 -
Differentiation of Asthma/COPD Exacerbation and Stable State Using Automated Lung Sound Analysis With LungPass Device
|