Quantification of Internal Training Load

Resistance Training Clinical Trial

— QUADRATURE  

Official title:

Quantification of Internal Training Load: Toward the Prediction of the Distribution of Hypertrophy

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT06164249
• Other study ID #: EM_LL_2024
• Status: Not yet recruiting
• Phase: N/A
• Start date: January 29, 2024
• Est. completion date: May 19, 2024

Study information

• Verified date: December 2023
• Source: Université de Nantes
• Contact: Lilian LACOURPAILLE, Doctor
• Phone: +33670807473
• Email: lilian.lacourpaille[@]univ-nantes.fr
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The aim of this study is to determine whether the distribution of internal load predicts the distribution of muscle hypertrophy among hamstring heads after a 10-week resistance exercise program. The hypothesis is that the distribution of internal muscle load among the hamstring is related to the distribution of muscle hypertrophy.

Description:

It is well accepted that muscle stress (mechanical and/or metabolic) is the major way to induce muscle hypertrophy. While this link between muscle stress and hypertrophy is pivotal is sport training, prevention and rehabilitation, it remains poorly understood. To date, the only indirect evidence of relationship of muscle stress and muscle hypertrophy is the similar patterns (from independent studies) between muscle damage and hypertrophy within quadriceps (i.e., rectus femoris (RF) > vastus (VL) = vastus medialis VM), hamstring, and triceps surae. However, muscle damage is an indirect proof of muscle mechanical stress. With the quantification of internal muscle load, it is interesting to determine whether the muscle that receives the larger stress exhibits the larger hypertrophy.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 36
• Est. completion date: May 19, 2024
• Est. primary completion date: April 2, 2024
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 25 Years

Eligibility

Inclusion Criteria:

• No history of lower limb injury

• No chronic pathology associated with a long term care

Exclusion Criteria:

• Individual enrolled in a research study

Related Conditions & MeSH terms

• Hypertrophy
• Muscle
• Resistance Training

Intervention

Other:
• strength training
Strength training, three times a week, during nine weeks.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Université de Nantes

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Muscle volume	Hypertrophy	10 weeks
Primary	Internal training load	Magnitude and onset/offset of muscle activation	10 weeks
Secondary	Maximal strength Nordic	Maximal strength during the Nordic exercise	10 weeks
Secondary	Maximal strength Deadlift	Maximal strength during the Deadlift exercise	10 weeks