Resistance Exercise Training in Children.

Resistance Training Clinical Trial

Official title:

The Effects of Resistance Exercise on Muscle Activation and Lipids in Children

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT06078358
• Other study ID #: STUDY00147248
• Status: Completed
• Phase: N/A
• Start date: August 2, 2021
• Est. completion date: September 6, 2023

Study information

• Verified date: October 2023
• Source: University of Kansas Medical Center
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is examine the effects of 8 weeks (3 days/week) of resistance exercise training in children 8 to 10 years of age on muscle strength, activation, and lipids of the vastus lateralis.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 32
• Est. completion date: September 6, 2023
• Est. primary completion date: September 6, 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 8 Years to 10 Years

Eligibility

Inclusion Criteria:

• Healthy volunteer males and females ages 8 - 10 years.

Exclusion Criteria:

• No history or ongoing neuromuscular diseases, musculoskeletal injuries, or a disease that effects metabolism.

Related Conditions & MeSH terms

• Resistance Training

Intervention

Other:
• Resistance exercise training
Traditional linear periodization resistance training.

Locations

Country	Name	City	State
United States	Energy Balance Laboratory	Kansas City	Missouri
United States	Hoglund Biomedical Imaging Center	Kansas City	Kansas
United States	Exercise and Human Performance Laboratory	Overland Park	Kansas
United States	Metabolic and Body Composition Laboratory	Overland Park	Kansas

Sponsors (2)

Lead Sponsor	Collaborator
University of Kansas Medical Center	National Strength and Conditioning Association

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	Change from baseline in the fatty acid saturation levels of the extramyocellular lipids of the vastus lateralis, as measure with magnetic resonance spectroscopy	The score will reflect a saturation level of fatty acids in the extramyocellular lipid. The higher score, reflects greater fatty acid saturation.	baseline, following the intervention (9 weeks)
Other	Change from baseline in the fatty acid saturation levels of the intramyocellular lipids of the vastus lateralis, as measure with magnetic resonance spectroscopy	The score will reflect a saturation level of fatty acids in the intramyocellular lipid. The higher score, reflects greater fatty acid saturation.	baseline, following the intervention (9 weeks)
Other	Change from baseline in motor unit firing rates during a 35% of maximal voluntary contraction (MVC).	Scores are measured with the y-intercepts from the firing rates versus recruitment threshold relationships from the 35%. The higher y-intercept score reflects greater muscle activation.	baseline, following the intervention (9 weeks)
Other	Change from baseline in motor unit firing rates during a 35% of maximal voluntary contraction (MVC).	Scores are measured with the slopes from the firing rates versus recruitment threshold relationships from the 35%. The higher slope score reflects greater muscle activation.	baseline, following the intervention (9 weeks)
Other	Change from baseline in intramyocellular lipids of the vastus lateralis, as measure with magnetic resonance spectroscopy	The score will reflect a concentration. The higher score, reflects more fat in the fibers.	baseline, following the intervention (9 weeks)
Other	Change from baseline in extramyocellular lipids of the vastus lateralis, as measure with magnetic resonance spectroscopy	The score will reflect a concentration. The higher score, reflects more fat in the fibers.	baseline, following the intervention (9 weeks)
Primary	Change in the muscular strength of leg extensors, as measured with isometric strength.	The score will reflect the strength of the leg extensors. The higher score, reflects greater muscular strength.	baseline, following the intervention (9 weeks)
Secondary	Change from baseline in motor unit firing rates during a 60% of maximal voluntary contraction (MVC).	Scores are measured with the y-intercept from the firing rates versus recruitment threshold relationships from the 60%. The higher y-intercept score reflects greater muscle activation.	baseline, following the intervention (9 weeks)
Secondary	Change from baseline in motor unit firing rates during a 60% of maximal voluntary contraction (MVC).	Scores are measured with the slope from the firing rates versus recruitment threshold relationships from the 60%. The higher slope score reflects greater muscle activation.	baseline, following the intervention (9 weeks)
Secondary	Change from baseline in thigh muscle cross-sectional area.	Scores are measured cross-sectional area from ultrasound images.	baseline, following the intervention (9 weeks)