Clinical Trials Logo
  1. Home
  2. Residual Neuromuscular Blockade
  3. NCT02939911

Residual Neuromuscular Blockade in Pediatric Anesthesia — REPEB  

Residual Neuromuscular Blockade Clinical Trial

Official title:
Residual Neuromuscular Blockade in Paediatric Patients Before Extubation and in Postanesthetic Care Unit:Prospective Observational Cohort Study

Clinical Trial Summary

Residual neuromuscular blockade (RNB) is frequent and it is associated with postoperative morbidity and mortality. The incidence of the RNB in pediatric anesthesia is currently not known. The aim of this prospective observational cohort study is to evaluate the early RNB just before extubation and late RNB at the time of arrival to postanesthetic care unit (PACU).

Clinical Trial Description

Residual neuromuscular blockade (RNB) is frequent and it is associated with negative impact on postoperative morbidity and mortality. The incidence of the RNB in adult is well described, however in pediatric subpopulation it is currently not known. The aim of this prospective observational cohort study is to evaluate the early RNB just before extubation and late RNB at the time of arrival to postanesthetic care unit (PACU). In the trial will be enrolled all pediatric patients (28 weeks of age and older - 19 years old) whom will be administered neuromuscular blocking agent during anesthesia. The demographic data will be collected including: age, weight, type of surgery, ASA status. The anesthesia management will be described including: airway management, type and cumulative dose of neuromuscular blocking agent (NMBA) and time and dose of the last administered bolus of NMBA. The residual neuromuscular blockade will be measured according to the standards: TOF Watch accelerometry at the moment prior to extubation (two measurements) in TOF mode and at the arrival to postanesthetic care unit (PACU) (two measurements) in TOF mode. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02939911
Study type Observational
Source Brno University Hospital
Contact
Status Completed
Phase
Start date January 2017
Completion date December 2017
View Details
See also
  Status Clinical Trial Phase
Enrolling by invitation NCT04619225 - Cardiac Output and Recovery Time N/A
Recruiting NCT05992090 - Neuromuscular Blockade Monitoring Using Kine-myography vs Electromyography.
Completed NCT02146859 - Predictor of Residual Neuromuscular Blockade in Recovery Room After General Anesthesia
Completed NCT03585400 - Validation of the REPS Prediction Tool
Terminated NCT01678625 - Electromyographic Assessment of Onset and Recovery of Neuromuscular Blockade
Completed NCT03417804 - Incidence of Postoperative Residual Neuromuscular Blockade in Portugal
Completed NCT03111082 - Incidence of Postoperative Neuromuscular Blockade in Post-Anesthesia Care Unit at Parkland Hospital: Does Size Matter?
Completed NCT04244266 - Observational Study in Bariatric Surgery
Completed NCT02660398 - Incidence and Severity of Residual Neuromuscular Blockade Phase 4
Completed NCT03920670 - Comparison of the ToFscan and TetraGraph During Recovery of Neuromuscular Function in the Post Anesthesia Care Unit N/A
Completed NCT01837498 - Reversal of Neuromuscular Blockade in Thoracic Surgical Patients
Completed NCT02213848 - Effect of Calcium Chloride on Recovery From Neuromuscular Blockade N/A
Completed NCT04352127 - Visual and Electromyography Assessments in Response to Train-of-Four Stimulation of the Ulnar Nerve N/A
Completed NCT04312256 - Thumb vs Great Toe Recovery N/A
Completed NCT04352140 - Electromyographic and Acceleromyographic Monitoring in Restricted Arm Movement Surgical Setting N/A
Withdrawn NCT03574337 - Residual Neuromuscular Blockade in Cardiac Surgery Patients Phase 4