Resection Cavity Clinical Trial
Official title:
Assessment of Neurosensory Function Following Segmental Mandibular Resection of Non-malignant Lesions With Inferior Alveolar Nerve Preservation: A Case Series Trial
This study wInclusion criteria for this study will be as follows:
- Age group: from 15 to 60 years old.
- Patients with with non malignant mandibular neoplasms indicated for segmental resection.
Exclusion criteria:
- Patients with malignant mandibular neoplasms.
All cases will undergo surgery under general anesthesia. The mandibular lesion will be
segmentally resected. The cuts will be performed with the aid of the prefabricated digital
template. The neurovascular bundle will be separated and protected. Then reconstruction will
be performed.
Postoperative patient evaluation:
Neurosensory examination:
Assessment of the inferior alveolar nerve function will be performed preoperatively, 2 and 12
weeks postoperatively through Trigeminal somatosensory evoked potential technique. Six months
postoperatively by CBCT for assessment of recurrence
This study will include 10 patients complaining from non malignant mandibular lesions.
nopatients will be selected from the outpatient clinic of the Oral & Maxillofacial Surgery
department, faculty of Dental Medicine Cairo University.
All the procedures will be explained for all patients before undergoing operation and
informed consent process will be taken, this study will be displayed to the research ethics
committee to obtain approval.
Inclusion criteria for this study will be as follows:
- Age group: from 15 to 60 years old.
- Patients with with non malignant mandibular neoplasms indicated for segmental resection.
Exclusion criteria:
- Patients with malignant mandibular neoplasms. 1- Pre-operative phase
Patients will be subjected to:
Case history including personal data, medical, a-surgical and family history b-Clinical
examination c.Radiographic examination using orthopantogram, and computed tomography (CT)
Preoperative anesthesia assessment for fitness for general anesthesia.d Treatment planning
and fabrication of the digital template.e 2 -Operative phase All cases will undergo surgery
under general anesthesia. The mandibular lesion will be segmentally resected. The cuts will
be performed with the aid of the prefabricated digital template. The neurovascular bundle
will be separated and protected. Then reconstruction will be performed.
3-Postoperative care:
Postsurgical instructions and follow up:
Proper postoperative instructions will be given the patient, in addition to the postoperative
medications including antibiotics, corticosteroids and analgesics.
Postoperative patient evaluation:
Neurosensory examination:
Assessment of the inferior alveolar nerve function will be performed preoperatively, 2 and 12
weeks postoperatively through Trigeminal somatosensory evoked potential technique. Six months
postoperatively by CBCT for assessment of recurrence.
Statistical analysis:
Data will be analyzed using IBM SPSS advanced statistics (Statistical Package for Social
Sciences), version 21 (SPSS Inc. Chicago). The data will be compared using paired t-test.
;
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT05160818 -
Hypofractionated Versus Single Fraction Stereotactic Adjuvant Radiotherapy to the Resection Cavity of Brain Metastases
|
N/A |