Reperfusion Injury Clinical Trial
Official title:
Pulmonary Protection of Transcutaneous Electrical Acupoint Stimulation in Gynecologic Laparoscopic Surgery
TEAS might protect against postoperative pulmonary such as ischemia-reperfusion injury (IRI) and atelectasis. We tested the hypothesis that transcutaneous electrical acupoint stimulation protects against postoperative pulmonary complications in patients who are receiving mechanical ventilation during general anesthesia for gynecologic laparoscopic surgery.
Participants: 100 patients who underwent elective gynecologic laparoscopic surgery Methods: We recruited 100 patients who are planned for gynecologic laparoscopic surgery. Patients were enrolled from March 1, 2015. We randomly allocated patients into two groups: controlled group ( patients treated without transcutaneous electrical acupoint stimulation) and TEAS group (patients treated with TEAS on Feishu, Hegu, Chize half an hour before the surgery). Blood pH, Pco2, Po2 and oxygen saturation were measured by an automatic blood gas analyzer immediately after obtaining the samples from the aorta. Sample all the patients blood before and after the surgery. And then measure the level of TNF-α, IL-1β, and IL-6. ;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Prevention
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT02251041 -
Combined Drug Approach to Prevent Ischemia-reperfusion Injury During Transplantation of Livers (CAPITL)
|
Phase 2 | |
| Completed |
NCT01944605 -
Intestinal Ischemia as a Stimulus for Systemic Inflammatory Response After Cardiac Arrest
|
N/A | |
| Completed |
NCT00778323 -
Clinical Trial of Remote Preconditioning in Patients Undergoing Cervical Decompression Surgery
|
Phase 1/Phase 2 | |
| Completed |
NCT00529607 -
Diagnostics for the Reperfusion Injury Following MI
|
N/A | |
| Completed |
NCT00994981 -
Magnesium Administration in Liver Transplantation and Reperfusion Injury
|
Phase 4 | |
| Completed |
NCT02731651 -
Effect of Pneumoperitoneum on Human Ovary
|
N/A | |
| Completed |
NCT02286544 -
Effects of Oxygen Treatment on Mechanisms Involved in Ischemia-reperfusion Injury: A Pilot Study in Healthy Volunteers
|
Phase 1 | |
| Active, not recruiting |
NCT00189007 -
Antenatal Allopurinol During Fetal Hypoxia
|
Phase 3 | |
| Completed |
NCT01167569 -
Study of High Dose Vitamin C On Outcome in Cardiac Surgery Patients
|
Phase 4 | |
| Completed |
NCT00246740 -
Protection of the Heart With Doxycycline During Coronary Artery Bypass Grafting
|
Phase 2 | |
| Enrolling by invitation |
NCT05725694 -
Acute Ischaemic STROKE: From LAboratory to the Patient's BED
|
||
| Completed |
NCT00402506 -
A Safety and Efficacy Study to Confirm the Cardioprotective Effects of MC-1 in Patients Undergoing High-Risk CABG
|
Phase 3 | |
| Completed |
NCT03176823 -
Remote Ischemic Conditioning as a Treatment for Traumatic Brain Injury
|
N/A | |
| Completed |
NCT02512640 -
Comparison of Oxidative Stress Changes in Different Ventilation Strategies During Gynecologic Laparoscopic Surgery
|
N/A | |
| Recruiting |
NCT05574296 -
Hydrogen's Feasibility and Safety as a Therapy in ECPR
|
Phase 1 | |
| Active, not recruiting |
NCT02127996 -
GLP-1 Loading During Elective Percutaneous Coronary Intervention
|
Phase 2 | |
| Terminated |
NCT02394405 -
Myocardial and Renal Dysfunction by Oxidative Stress Caused by Cardiac Surgery
|
||
| Completed |
NCT00516711 -
Role of Volatile Anesthetics for Hepatic Protection
|
N/A | |
| Terminated |
NCT04316468 -
Cardiac Strain Using Speckle Tracking Echocardiography During Orthotopic Liver Transplantation
|
||
| Not yet recruiting |
NCT05676957 -
Reperfusion With Hypothermia in Acute Ischemic Stroke
|
N/A |