Role of Volatile Anesthetics for Hepatic Protection

Status Completed

Clinical Trial Summary

This study aims to evaluate the attenuation of ischemic-reperfusion injury in the liver after sevoflurane preconditioning. In the presence of sevoflurane, an attenuation of liver injury is hypothesized (diminished increase of liver enzymes, reduced production of inflammatory mediators).

Clinical Trial Description

Organ protection; preconditioning; volatile anesthetics; ischemia reperfusion ;

Study Design

Allocation: Randomized, Endpoint Classification: Pharmacodynamics Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention

Related Conditions & MeSH terms

Reperfusion Injury

Clinical Trial Details

NCT number	NCT00516711
Study type	Interventional
Source	University of Zurich
Contact
Status	Completed
Phase	N/A
Start date	March 2006
Completion date	December 2007

View Details

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