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The Impact of Magnesium Supplementation on Insulin Resistance and Secretion in Renal Transplant Recipients

Renal Transplantation Clinical Trial

Official title:
The Impact of Magnesium Supplementation on Insulin Resistance and Secretion in Renal Transplant Recipients

Clinical Trial Summary

Hypomagnesemia is common in renal transplant recipients and is mainly because of enhanced renal magnesium wasting, caused by immunosuppressive drugs (calcineurin inhibitors). Glucose metabolism disorders, including insulin resistance and decreased insulin secretion, are also prevalent post-transplantation and often precede the development of diabetes. As magnesium supplementation has been demonstrated to increase insulin sensitivity in both diabetic and non-diabetic patients, its potential therapeutic supplementation (post-transplantation) deserves further examination. The hypothesis is that magnesium supplementation in renal transplant recipients exerts a beneficial effect on insulin resistance and/or secretion.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01291030
Study type Interventional
Source University Hospital, Ghent
Contact
Status Completed
Phase N/A
Start date January 2011
Completion date December 2015
View Details
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