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Renal Transplant clinical trials

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NCT ID: NCT01380002 Recruiting - Liver Transplant Clinical Trials

Home-Care Needs in Liver or Renal Transplantation Recipients and Their Spouses

Start date: December 2010
Phase: N/A
Study type: Observational

- Liver/renal transplantations are now tending to be the most important treatment for terminal liver and renal disease. Although transplantation can prevent recipients from suffering with critical and fatal symptoms, patients may experience the complication from surgery and immunosuppressive drugs. Furthermore, they might have many unmet needs in daily life, and so as their spouses. The purpose of this study is to explore the home-care needs among the post liver or renal transplant recipients and their spouses, and identify the significant factors for care needs. - A cross-sectional correlated design will be used and patients will be recruited by purposive sampling from an organ transplant outpatient department at a medical center in northern Taiwan. A set of structured questionnaires will be used to collect data. - The result of this study will be helpful for clinical nurses to understand liver or renal recipients' physical and mental distress, also identify the potential risk of home-care needs and the degree of satisfaction as well.

NCT ID: NCT01234363 Recruiting - Renal Transplant Clinical Trials

Renal Allograft : Evaluation of Parenchymal Fibrosis by Elastography

GREFE
Start date: May 2010
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the potential of elastography for noninvasive assessment of fibrosis in renal allograft.

NCT ID: NCT00737659 Recruiting - Renal Transplant Clinical Trials

CellCept® Dose Adjustment Versus Fixed Dose (Standard Care) in Renal Transplant Recipients

MMF
Start date: August 2008
Phase: Phase 4
Study type: Interventional

In order to avoid renal transplant rejection, the immune system should be suppressed. After the renal transplant subjects are treated with a combination of two to four different types of immunosuppressive drugs. Theses drugs are very efficient in the prevention of the renal transplant rejection. Still, they can cause side effect. Research in renal transplant tries to find the best treatment in order to avoid renal rejection on one hand and to reduce as much as possible the undesired adverse and toxicity effects on the other hand. Therapeutic efficacy and the onset of adverse effects are influenced by levels of mycophenolic acid (MPA, the active metabolite of MMF, CellCept®). The primary objective of this study is to assess the treatment superiority of CellCept® Dose Adjustment treatment, based on individual MPA concentration value monitored periodically, against treatment with CellCept® Fixed Dose (standard care).