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Envarsus XR in African American Renal Transplant Recipients — EXR  

Renal Transplant Recipients Clinical Trial

Official title:
Envarsus XR in African American Renal Transplant Recipients

Clinical Trial Summary

The purpose of this study is to collect data prospectively on African American patients who are taking the immunosuppressant Envarsus post kidney transplant. We are looking to see if African American renal transplant recipients that receive Envarsus will have less tubular injury and calcenurin inhibitor toxicity compared with patients that receive tacrolimus IR.

African americans have the higher rates of CYP3A5 which is associated with the need of higher tacrolimus dose to achieve an adequate level and this many times is associated with signs and symptoms of tacrolimus toxicity such as tremors, headaches and neuropathies.

The retrospective cohort will be African American patients that will be matched by age, gender, type of kidney transplant (living vs deceased) and level of sensitization

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02956005
Study type Interventional
Source Georgetown University
Contact
Status Terminated
Phase N/A
Start date September 2016
Completion date September 2018
View Details
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