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Clinical Trial Details — Status: Recruiting

Administrative data

NCT number NCT01283880
Other study ID # ML6919
Secondary ID
Status Recruiting
Phase N/A
First received January 25, 2011
Last updated May 29, 2012
Start date May 2012
Est. completion date June 2013

Study information

Verified date January 2011
Source Universitaire Ziekenhuizen Leuven
Contact Pieter Evenepoel, MD
Phone 003216344580
Email pieter.evenepoel@uz.kuleuven.ac.be
Is FDA regulated No
Health authority Belgium: University Hospitals Leuven
Study type Observational

Clinical Trial Summary

Metabolic acidosis is a common complication in incident renal transplant recipients. Protracted acidosis may be associated with osteoporosis, inflammation, negative protein balance and malnutrition, and last but not least may cause renal dysfunction. Preliminary data indicate an increased prevalence of nephrocalcinosis in renal transplant biopsies of incident patients presenting with metabolic acidosis. The present study aims (1)evaluate the prevalence and type of renal tubular acidosis (RTA) in incident renal transplant recipients and to identify clinical correlates and (2) to find associations between RTA, nephrolithiasis and nephrocalcinosis


Recruitment information / eligibility

Status Recruiting
Enrollment 50
Est. completion date June 2013
Est. primary completion date June 2013
Accepts healthy volunteers No
Gender Both
Age group 18 Years to 80 Years
Eligibility Inclusion Criteria:

- Recipient of a single kidney transplant included in the protocol biopsy program.

- eGFR > 30 ml/min

- Age = 18 years

- Written informed consent

Exclusion Criteria:

Study Design

Observational Model: Cohort, Time Perspective: Prospective


Locations

Country Name City State
Belgium University Hospitals Leuven Leuven

Sponsors (1)

Lead Sponsor Collaborator
Universitaire Ziekenhuizen Leuven

Country where clinical trial is conducted

Belgium,