Leukemia Clinical Trial
Official title:
Renal Dysfunction With Low to Intermediate Dose Methotrexate in Acute Lymphoblastic Leukemia Treatment
RATIONALE: Gathering information about how often kidney dysfunction occurs in children and
young adults receiving methotrexate for acute lymphoblastic leukemia may help doctors learn
more about the disease and plan the best treatment.
PURPOSE: This research study is looking at kidney dysfunction in children and young adults
who have received low-dose or intermediate-dose methotrexate for acute lymphoblastic
leukemia.
OBJECTIVES:
- Examine the incidence of renal dysfunction in children and young adults being treated
for acute lymphoblastic leukemia with low- to intermediate-dose methotrexate.
OUTLINE: Medical charts are reviewed to obtain the following information: gender, age,
diagnosis, regimen, day of therapy, renal function, creatinine level, mucositis, skin
sloughing, methotrexate level at highest level, and number of days after intravenous
methotrexate.
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