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Clinical Trial Summary

This is a Phase 1, non-randomized, open-label, 2-part study to investigate the effect of renal impairment on the pharmacokinetics (PK), safety and tolerability of a single oral dose of PF-07321332 in combination with the PK boosting agent ritonavir. Participants will be selected and categorized into normal renal function or renal impairment groups based on their estimated glomerular filtration rate. Part 1: will be conducted in approximately 24 participants (approximately 8 per group) with stable mild or moderate renal impairment and a control group of participants with normal renal function. Part 2 will be conducted in approximately 8 participants with stable severe renal impairment.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04909853
Study type Interventional
Source Pfizer
Contact
Status Completed
Phase Phase 1
Start date June 15, 2021
Completion date October 7, 2021

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