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Clinical Trial Summary

This is a Phase I, open-label study evaluating the PK of S-1 components and their metabolites in patients with advanced solid tumors and varying degrees of renal function. Patients will be stratified by baseline 24-hour creatinine clearance(CrCL) into 4 cohorts using the normal clearance formula: Group A: Control Group B:Mild renal dysfunction Group C:Moderate renal function and Group D: Severe renal dysfunction. Six patients will be enrolled into each cohort.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT00398307
Study type Interventional
Source Taiho Oncology, Inc.
Contact
Status Completed
Phase Phase 1
Start date February 2006
Completion date September 2010

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