Cardiac Surgery Clinical Trial
Official title:
Renal Resistive Index Compared With NephroCheckTM to Predict Postoperative Acute Renal Failure in Patients Undergoing Cardiac Surgery.
Postoperative acute renal failure is a frequent complication after cardiac surgery. The
current practice cannot predict Acute Kidney Injuries (AKI) early enough to reduce a
significant kidney assault and prevent an organic dysfunction leading to cortical tubular
necrosis.
Several recent studies in cardiac surgery have shown that, both sonographic criteria, such
as the Renal Resistive Index (IRR) and urinary biomarkers can predict AKI promptly. These
urinary biomarkers are the 'tissue inhibitor of metalloproteinases' (TIMP-2) and the
'insulin-like growth factor binding protein' (IGFBP7). These two proteins are sought
noninvasively, directly in the urine, within the same test called 'NephroCheckTM'. These
markers, ultrasonographic and biologic, have the advantage of being easy to perform,
accessible and seem to have both high sensitivity and specificity to predict AKI promptly
after cardiac surgery. Thus, the IRR and the NephroCheckTM test could become essential tests
to guide clinicians in determining rapidly whether a patient will develop AKI. However, so
far, no study has compared these markers yet.
Therefore, the aim of this prospective observational study will be to compare the
effectiveness of the IRR with the NephroCheckTM to predict AKI promptly after cardiac
surgery. The secondary outcome will be to determine the threshold of these markers from
which patients will be likely to develop AKI
n/a
Observational Model: Cohort, Time Perspective: Prospective
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05054179 -
Pecto-Intercostal Fascial Plane Block Catheter Trial for Reduction of Sternal Pain
|
Phase 2/Phase 3 | |
| Completed |
NCT04051021 -
Non-Pharmacological Interventions on Patient Experience and Healthcare Utilization in Adult Cardiac Surgery Patients
|
N/A | |
| Recruiting |
NCT04604886 -
The Consistency of Cardiac Output Measured by Pulmonary Artery Catheter and LiDCO in Cardiac Surgical Patients
|
N/A | |
| Recruiting |
NCT04075981 -
Prevention Atrial Fibrillation by BOTulinum Toxin Injections (BOTAF)
|
Phase 3 | |
| Completed |
NCT04062396 -
Comparison of Remowell 2 and Inspire on Delirium and Cognitive Dysfunction
|
N/A | |
| Recruiting |
NCT04709705 -
DMSO Cryopreserved Platelets in Cardiopulmonary Bypass Surgery (CRYPTICS)
|
Phase 2/Phase 3 | |
| Not yet recruiting |
NCT05563662 -
SURgical Registry of ENDocarditis EuRope
|
||
| Withdrawn |
NCT03289104 -
Improving Sternal Healing After Cardiac Surgery: Sternal Wire vs ZIPFIX
|
N/A | |
| Completed |
NCT04199039 -
Effects of Endotracheal Tube Fixation Methods on Hemodynamic Parameters During Endotracheal Suction
|
N/A | |
| Completed |
NCT02964026 -
Study of Clinical Outcomes Associated With the Pulmonary Artery Catheter (PAC) in Cardiac Surgery Patients
|
N/A | |
| Completed |
NCT03563196 -
Diagnosis Of Pulmonary Complications After Cardiac Surgery In Children
|
||
| Completed |
NCT02471001 -
The Levels of Anaesthetics in Heart Muscle During Heart Surgery
|
N/A | |
| Completed |
NCT01246947 -
Tricuspid Annuloplasty for Moderate Tricuspid Regurgitation Associated With Miral Operation
|
N/A | |
| Completed |
NCT01151254 -
Comparison of Propofol Based Versus Volatile Based Anesthesia and Postoperative Sedation
|
N/A | |
| Completed |
NCT00996099 -
Continuous Glucose Monitoring Combined With Computer Algorithm for Intensive Insulin Therapy in Cardiosurgical Patients
|
N/A | |
| Completed |
NCT00821262 -
Sevoflurane in Cardiac Surgery
|
Phase 4 | |
| Completed |
NCT00617955 -
Effects of Aprotinin During Cardiac Surgery/Long Term Death Rates
|
N/A | |
| Completed |
NCT00336466 -
The Erythropoietin NeuroProtective Effect: Assessment in CABG Surgery (TENPEAKS)
|
Phase 2 | |
| Completed |
NCT00337805 -
Double Blind Randomized Trial of Saline vs Pentaspan for Resuscitation After Cardiac Surgery
|
Phase 2/Phase 3 | |
| Recruiting |
NCT04978636 -
Low Tidal Volume Ventilation With Hyperoxia Avoidance During Cardiopulmonary Bypass (The FOCUS Trial)
|
N/A |