Renal Failure Clinical Trial
Official title:
Assessment of the Safety and Efficacy of Fondaparinux as an Anticoagulant in Haemofiltration in Patients With Acute Renal Failure.
The purpose of this project is to assess the safety and effectiveness of fondaparinux, a new drug to prevent blood clotting in the continuous dialysis machine used in intensive care patients who have kidney failure.
The study hypothesis is that when used as an anticoagulant in haemofiltration, fondaparinux
prolongs the filter life when compared to enoxaparin.
Fondaparinux is the first compound of a new class of synthetic oligosaccharides with
antithrombotic effects. It represents the active portion of the natural heparin molecule.
The null hypothesis is that there is no difference in filter life when using fondaparinux or
enoxaparin as anticoagulation for haemofiltration.
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