Evaluation of Gadoterate in Patients With Decreased Kidney Function

Status Active, not recruiting

Clinical Trial Summary

This study is for individuals with decreased kidney function whose doctor has ordered Magnetic Resonance Imaging (MRI). Because kidney function is decreased, these patients usually do not receive the intravenous contrast material that can improve the accuracy of the MRI findings. The purpose of this study is to evaluate the safety and benefit of using a contrast material called Gadoterate in patients with decreased kidney function.

Clinical Trial Description

Gadolinium-based intravenous contrast agents are widely used for the enhancement of MRI findings. However, these agents have been implicated in varying degrees of nephrotoxicity and therefore are not usually used in patients with renal dysfunction. Gadoterate is a Gadolinium agent and previous studies have indicated that it is safe in patients with decreased kidney function. The purpose of this study is to evaluate the safety and efficacy of using Gadoterate in this patient population.

Participants who have been scheduled for an MRI will choose to either receive Gadoterate contrast as part of their MRI or not receive Gadoterate as part of their MRI. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02382380
Study type	Interventional
Source	Loyola University
Contact
Status	Active, not recruiting
Phase	Phase 4
Start date	March 2015
Completion date	July 2020

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT00972569` - Low Dose Intravenous (IV) Infusion of BNP in the Presence and Absence of Acute Type V Phosphodiesterase (PDE V) in Improving Renal Function in Hospitalized Chronic Heart Failure (CHF) Patients With Renal Dysfunction	Phase 1/Phase 2
Completed	`NCT02083133` - Insulin Dosing in Diabetic Patients With End Stage Renal Disease (ESRD) or Hemodialysis
Completed	`NCT01131845` - The Effect of Renal Impairment on the Pharmacokinetics of Oral Treprostinil	Phase 1
Completed	`NCT03540511` - Postoperative Troponin in Renal Dysfunction After Cardiac Surgery
Completed	`NCT04788394` - Renal Involvement in Hospitalized Children With COVID-19
Completed	`NCT01368822` - Effect of Obesity on Long-term Clinical Outcomes After Kidney Donation	N/A
Completed	`NCT00308906` - Identification of Gene and Protein Markers of Kidney Injury in Aminoglycoside-treated Children	N/A
Recruiting	`NCT05941624` - Comparison Between HA330 Hemoperfusion Filter Hemodialysis and Conventional High-Flux Hemodialysis Filter	N/A
Completed	`NCT00390624` - Prevention Of Nephrotoxicity Following Bone Marrow Transplantation Using Urodilatin and Mannitol	Phase 2
Completed	`NCT04935294` - Study of Danicopan in Participants With Normal Kidney Function and Participants With Kidney Dysfunction	Phase 1
Not yet recruiting	`NCT04195126` - Early Haemadsorption in Major Burns	N/A
Completed	`NCT01704482` - N-acetylcysteine for Renal Protection in Patients With Rheumatic Heart Disease Undergoing Valve Replacement	Phase 2
Terminated	`NCT00818701` - Study of Low Dose Nesiritide With or Without Sildenafil in Congestive Heart Failure Patients With Renal Dysfunction	Phase 1
Completed	`NCT03856476` - The Effect of Childhood Dyslipidemia on Endothelial and Renal Function