Effects of Continuous Venous Dialysis and Hemodialysis on Fluid Dynamics by Bioreactance Method

Renal Dialysis Clinical Trial

Official title:

Investigation of the Effects of Continuous Venous Dialysis and Hemodialysis on Fluid Dynamics by Bioreactance Method

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03905122
• Other study ID #: TUTF-BAEK 2018/229
• Status: Completed
• Start date: June 15, 2018
• Est. completion date: June 15, 2020

Study information

• Verified date: October 2020
• Source: Trakya University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Dialysis methods applied at the bedside and dialysis methods applied in hemodialysis unit are widely applied in patients with renal insufficiency. Especially hemodynamically affected patients are less affected by hemodynamics as a result of using dialysis methods. It is a completely non-invasive method by bioreactance method and it can be done to measure the intra-body fluid status with the help of the glued probes. The aim of this study is to investigate the effects of continuous venous dialysis and hemodialysis on the fluid dynamics applied at the bedside with bioreactance method. In this way, the patient can develop more comfortable hemodynamic changes. Patients in the Surgery, Reanimation and Postoperative Intensive Care Unit with more than 24 hours of hospitalization and bedside dialysis or hemodialysis will be included in the study. Before the dialysis, body fluid measurements will be made with bioreactance, and after dialysis in patients receiving hemodialysis, and in dialysis patients 6, 12, 24 and 36 hours.

Description:

Dialysis methods applied at the bedside and dialysis methods applied in hemodialysis unit are widely applied in patients with renal insufficiency. Especially hemodynamically affected patients are less affected by hemodynamics as a result of using dialysis methods. Dialysis in the hemodialysis unit is a method used in intensive care patients and is preferred especially in patients with stable hemodynamics. In dialysis methods, changes occur frequently in the body fluids of the patient. It is a completely non-invasive method by bioreactance method and it can be done to measure the intra-body fluid status with the help of the glued probes. The aim of this study is to investigate the effects of continuous venous dialysis and hemodialysis on the fluid dynamics applied at the bedside with bioreactance method. As a result of measurements with buioreactans method, fluid balance in patients will be understood more easily. In this way, the patient can develop more comfortable hemodynamic changes. Patients in the Surgery, Reanimation and Postoperative Intensive Care Unit with more than 24 hours of hospitalization and bedside dialysis or hemodialysis will be included in the study. Before the dialysis, body fluid measurements will be made with bioreactance, and after dialysis in patients receiving hemodialysis, and in dialysis patients 6, 12, 24 and 36 hours.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 60
• Est. completion date: June 15, 2020
• Est. primary completion date: June 15, 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 90 Years

Eligibility

Inclusion Criteria:

• patients required dialysis therapy

Exclusion Criteria:

• under 18 years old

• confirmed or undiagnosed brain death

Related Conditions & MeSH terms

• Renal Dialysis

Intervention

Device:
• bioreactans tool
It is a completely non-invasive method by bioreactance method and it can be done to measure the intra-body fluid status with the help of the probes.

Locations

Country	Name	City	State
Turkey	Trakya University	Edirne

Sponsors (1)

Lead Sponsor	Collaborator
Trakya University

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	change in thoracic fluid content	change in thoracic fluid content	before and after hemodialysis therapy, before bedside continous venovenous dialysis therapy and 6,12,24 and 36. hours
Primary	change in Cardiac Output	change in Cardiac Output	before and after hemodialysis therapy, before bedside continous venovenous dialysis therapy and 6,12,24 and 36. hours
Primary	change in Cardiac Index	change in Cardiac Index	before and after hemodialysis therapy, before bedside continous venovenous dialysis therapy and 6,12,24 and 36. hours
Primary	change in stroke volum	change in stroke volum	before and after hemodialysis therapy, before bedside continous venovenous dialysis therapy and 6,12,24 and 36. hours