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NCT01002937 Clinical Trial

Novel Prognostic Markers in Renal Cancer

Renal Cell Carcinoma Clinical Trial

Official title:
Novel Prognostic Markers in Renal Cancer: a Protocol for the Analysis of Paraffin Embedded Tumour Samples

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT01002937
Other study ID # CCR3076
Secondary ID
Status Completed
Phase
First received
Last updated
Start date December 1, 2008
Est. completion date December 17, 2014

Study information
Verified date June 2024
Source Royal Marsden NHS Foundation Trust
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The purpose of this project is to analyze tumour tissue from a group of subjects with renal cell carcinoma, who have been treated at the Royal Marsden Hospital.

Description:

Renal cancers have different clinical outcomes. The principal research objective is to study tumour tissue from renal cancer patients and try and understand why some cancers progress more rapidly than others. Further, another key aim of this study is to try and understand why some patients respond to treatment and others do not.

Recruitment information / eligibility
Status Completed
Enrollment 182
Est. completion date December 17, 2014
Est. primary completion date December 17, 2014
Accepts healthy volunteers No
Gender All
Age group N/A and older
Eligibility Inclusion Criteria: - The presence of histologically proven renal cell cancer - The availability of paraffin embedded tissue - Informed consent needed for tissue taken after January 2006 (date of enforcement of human tissue act) Exclusion Criteria: - Absence of histological tissue - Absence of consent to study tissue after January 2006

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
United Kingdom The Royal Marsden NHS Foundation Trust Sutton Surrey

Sponsors (1)
Lead Sponsor Collaborator
Royal Marsden NHS Foundation Trust

Country where clinical trial is conducted

United Kingdom, 

Outcome
Type Measure Description Time frame Safety issue
Primary The profiling of the expression of signal transduction biomarkers, gene expression, gene copy numbers and effect of mutations of the VHL gene in renal cancer and their relationship to clinical outcomes. 5 years
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