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Clinical Trial Summary

Patients with relapsed/refractory acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) will receive lymphodepleting chemotherapy (Flu/Cy) and two infusions of cytokine-induced memory-like NK cells at the previously defined maximum tolerated dose (MTD), fourteen days apart. Low dose rhIL-2 will be administered to patients for in vivo expansion following cell infusion. Patients will be assessed for anti-leukemic efficacy and safety. Re-infusion of patients who relapsed after clinical response will be considered.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04893915
Study type Interventional
Source Washington University School of Medicine
Contact
Status Withdrawn
Phase Phase 2
Start date June 30, 2022
Completion date December 31, 2024

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