Effects of Early Sensory Reeducation Programs Using Mirror Therapy for Patients With Peripheral Nerve Injuries

Rehabilitation Clinical Trial

Official title:

A Touch-Observation and Task-based Mirror Therapy Protocol (MTPTOT) to Improve Sensorimotor Control and Functional Capability of Hands for Patients With Peripheral Nerve Injury

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02768857
• Other study ID #: B-ER-102-389
• Status: Completed
• Phase: N/A
• First received: May 5, 2016
• Last updated: May 12, 2016
• Start date: December 2014
• Est. completion date: October 2015

Study information

• Verified date: May 2016
• Source: National Cheng-Kung University Hospital
• Contact: n/a
• Is FDA regulated: No
• Health authority: Taiwan: Department of Health
• Study type: Interventional

Clinical Trial Summary

This study evaluated the effects of an integrated program of touch-observation and task-based mirror therapy on sensorimotor function in nerve injury patients. Before the return of protective sense (Value of Semmes-Weinstein monofilament test > 4.31), half of the participants received 15 minutes of mirror therapy program, followed by 20 minutes of regular hand therapy and 20 minutes of physiotherapy.While the other half received 15 minutes protective sensory reeducation programs, 20 minutes of regular hand therapy and 20 minutes of physiotherapy in each treatment session. Once the patients had regained the protective sense (Value of Semmes-Weinstein monofilament test < 4.31), the discriminative sensory reeducation program was started for the participants in both groups. The hypothesis was that using the mirror therapy for sensorimotor reeducation in the early phase after nerve repair would yield better results with regard to the returning of sensation, sensorimotor control ability and hand function than using a classical reeducation program alone.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 12
• Est. completion date: October 2015
• Est. primary completion date: October 2015
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 20 Years and older

Eligibility

Inclusion Criteria:

• median or ulnar nerve injury,

• a combination of nerve and tendon or vascular injury,

• injury sites between the level of mid-palm and elbow, and

• the protective sensation of the hand is lacking or impaired.

Exclusion Criteria:

• patients with deficits in cognition or language comprehension, as well as severe limitations in the range of motion of the upper limbs.

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Motor Deficit
• Peripheral Nerve Injuries
• Rehabilitation
• Sensation Disorders

Intervention

Behavioral:
• Sensorimotor reeducation programs

Locations

Country	Name	City	State
Taiwan	National Cheng-Kung University Hospital	Tainan

Sponsors (1)

Lead Sponsor	Collaborator
National Cheng-Kung University Hospital

Country where clinical trial is conducted

Taiwan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change from baseline result of Semmes-Weinstein monofilament (SWM) test at 12 weeks and 24 weeks		baseline, 12 weeks and 24 weeks	No
Primary	Change from baseline result of Purdue pegboard test at 12 weeks and 24 weeks		baseline, 12 weeks and 24 weeks	No
Primary	Change from baseline result of Minnesota manual dexterity test at 12 weeks and 24 weeks		baseline, 12 weeks and 24 weeks	No
Primary	Change from baseline result of Pinch-holding-up-activity (PHUA) test at 12 weeks and 24 weeks		baseline, 12 weeks and 24 weeks	No
Secondary	Change from baseline result of Static two-point discrimination (S2PD) test at 12 weeks and 24 weeks		baseline, 12 weeks and 24 weeks	No