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Efficacy of Panobinostat in Patients With Relapsed and Bortezomib-refractory Multiple Myeloma — MACS1271  

Refractory Multiple Myeloma Clinical Trial

Official title:
A Phase II, Multi-center, Single Arm, Open Label Study of Panobinostat in Combination With Bortezomib and Dexamethasone in Patients With Relapsed and Bortezomib-refractory Multiple Myeloma

Clinical Trial Summary

This study is designed to assess the effectiveness of the combination of Panobinostat plus Bortezomib and Dexamethasone in patients with relapsed and bortezomib refractory Multiple Myeloma.

Clinical Trial Description

This is a phase II, two stage, single arm, open label, multi-center study of oral PAN in combination with BTZ/Dex in patients with relapsed and refractory multiple myeloma, who are bortezomib-refractory and have received at least 2 prior lines of therapy. Patients must have been exposed to an iMID (lenalidomide or thalidomide) and progressed on or within 60 days of their last BTZ-containing line of therapy. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01083602
Study type Interventional
Source Novartis
Contact
Status Completed
Phase Phase 2
Start date June 2010
Completion date February 2014
View Details
See also
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