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Refractory Glaucoma clinical trials

View clinical trials related to Refractory Glaucoma.

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NCT ID: NCT05521334 Completed - Refractory Glaucoma Clinical Trials

MicroPulse Transscleral Laser Cyclophotocoagulation With the Zig Zag Mode in Glaucoma.

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

This is a prospective single-arm clinical trial in which patients with neovascular or primary open angle glaucoma with uncontrolled intraocular pressure (despite maximal tolerated anti-glaucoma medical treatment) were selected for micro-pulse trans-scleral cyclophotocoagulation using an MP3 handpiece with Iridex Cyclo G6 Laser settings (2000mW of 810 nm infrared diode laser set on micro-pulse delivery mode with 31.3 % duty cycle). The laser will be delivered over three quadrants for 90 seconds for each quadrant (total 270 sec) in Zigzag mode sparing the fourth quadrant for either further intervention or a previous surgery performed. Follow up examination (for at least 6 months) will include assessment of IOP in terms of percentage of IOP reduction and sustainability of results, BCVA, and the number of medications post-operatively.

NCT ID: NCT05230355 Not yet recruiting - Refractory Glaucoma Clinical Trials

Comparison Between Two Techniques of Subthreshold Diode Laser Cyclophotocoagulation in Refractory Glaucoma

Start date: February 1, 2022
Phase: N/A
Study type: Interventional

The aim of this study is to assess the results of subliminal subthreshold transscleral diode cyclophotocoagulation in refractory glaucoma using the standard technique of 360 degree application and to compare the outcome with a modified technique both in terms of efficacy and safety.

NCT ID: NCT04921098 Recruiting - Refractory Glaucoma Clinical Trials

CPC in Adult Refractory Glaucoma

Start date: July 1, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the relative effectiveness and safety of diode laser cyclophotocoagulation procedure to reduce IOP and relieve pain in adult patients with refractory glaucoma.

NCT ID: NCT04303897 Completed - Refractory Glaucoma Clinical Trials

Real-world Evidence Study of XEN in Chinese Patients With Refractory Glaucoma

Start date: December 19, 2019
Phase:
Study type: Observational

Real-world evidence study to assess the safety and effectiveness of XEN® Glaucoma Treatment System in Chinese patients with refractory glaucoma. Participants will be (prospective) or have already been (retrospective) implanted with XEN via specific urgent medical need.

NCT ID: NCT01404364 Completed - Refractory Glaucoma Clinical Trials

Use of Intravitreal Triamcinolone and Retrobulbar Chlorpromazine as Alternatives to the Management of Painful Blind Eye

Start date: January 2010
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the efficacy of intravitreal triamcinolone and retrobulbar chlorpromazine as alternatives in the management of ocular pain in blind eyes.

NCT ID: NCT01128699 Recruiting - Refractory Glaucoma Clinical Trials

Ahmed Valve Glaucoma Implant With Adjunctive Subconjunctival Bevacizumab in Refractory Glaucoma

Start date: May 2010
Phase: Phase 3
Study type: Interventional

The investigators aim to demonstrate the efficacy and safety of subconjunctival injection of Avastin as an adjunctive therapy for Ahmed valve glaucoma implant in patients with refractory glaucoma.

NCT ID: NCT00971061 Completed - Refractory Glaucoma Clinical Trials

Ahmed Glaucoma Valve and Single-Plate Molteno Implants in Treatment of Refractory Glaucoma

Start date: January 2003
Phase: Phase 3
Study type: Interventional

The purpose of this study is to investigate the efficacy and safety of the Ahmed valve implant (AVI) and the Molteno single-plate implant (MSPI) in eyes with refractory glaucoma during a follow-up period of 24 months.

NCT ID: NCT00893490 Recruiting - Refractory Glaucoma Clinical Trials

Ahmed Glaucoma Valve Alone, With Amniotic Membrane or With Mitomycin C (MMC) for Treatment of Refractory Glaucoma

Start date: n/a
Phase: Phase 1
Study type: Interventional

This randomized, controlled trial (RCT) compares the efficacy and safety of Ahmed Glaucoma Valve (AGV) implantation alone, with 3 minutes MMC application or with a single layer coverage of amniotic membrane. Outcomes include intraocular eye pressure (IOP), postoperative glaucoma medication and complications. AGV implantation site will be superior or inferior based on indication and these groups will be randomized separately.

NCT ID: NCT00349414 Recruiting - Refractory Glaucoma Clinical Trials

Safety Study of Conventional Versus Micropulse Transscleral Cyclophotocoagulation in Treating End-Stage Glaucoma

Start date: July 2006
Phase: Phase 1/Phase 2
Study type: Interventional

The aim of this study is to compare the safety and efficacy of conventional and micropulse transscleral diode laser in the treatment of end-stage glaucoma.