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Clinical Trial Summary

Mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy (MOGHE) is a new entity frequently associated with refractory epilepsy and neurodevelopmental disorders. Recently, it has been associated to SLC35A2 (Solute Carrier Family 35 Member A2) brain mosaic pathogenic variants. In addition, patients with germline SLC35A2 pathogenic variants improve with galactose supplementation. Therefore, the investigators aim to elucidate whether d-galactose as an add-on treatment might improve epilepsy and developmental outcomes in patients with MOGHE.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04833322
Study type Interventional
Source Hospital Ruber Internacional
Contact Angel Aledo-Serrano, MD PhD
Phone 0034-913875250
Email aaledo@neurologiaclinica.es
Status Recruiting
Phase N/A
Start date January 15, 2021
Completion date October 1, 2021

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