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Analysis of Ocular Surface Microbiota in Dry Eye Patients After Refractive Surgery

Refractive Surgery Clinical Trial

Official title:
Analysis of Ocular Surface Microbiota in Dry Eye Patients After Refractive Surgery

Clinical Trial Summary

By using 16S rRNA sequencing technology to analyze the changes in ocular surface microbiota before and after surgery, as well as the impact of changes in ocular surface microbiota on refractive surgery induced DES, new treatment ideas are provided for corneal refractive surgery induced DES patients, and the incidence of refractive surgery related DES is reduced.

Clinical Trial Description

This study aims to include 160 postoperative refractive surgery patients, who will be divided into a dry eye group and a normal group based on postoperative dry eye examination. Microbial samples of the patient's conjunctival sac will be collected, and changes in the ocular surface microbiota before and after surgery will be analyzed using 16S rRNA sequencing technology. The impact of changes in the ocular surface microbiota on refractive surgery induced DES will also be analyzed, providing new treatment ideas for corneal refractive surgery induced DES patients and reducing the incidence of refractive surgery related DES. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06448468
Study type Observational
Source Second Affiliated Hospital of Nanchang University
Contact yifeng yu
Phone 13979180258
Email 171018170@qq.com
Status Recruiting
Phase
Start date May 1, 2024
Completion date November 1, 2024
View Details
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