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Refractive Errors clinical trials

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NCT ID: NCT05656027 Completed - Presbyopia Clinical Trials

Phase 3 Evaluation of the Safety and Efficacy of LNZ101 for the Treatment of Presbyopia

CLARITY
Start date: December 19, 2022
Phase: Phase 3
Study type: Interventional

Phase 3 study to evaluate the safety and effectiveness of LNZ101 for the treatment of Presbyopia.

NCT ID: NCT05637827 Recruiting - Clinical trials for Myopia; Refractive Error

The Initiating Factors of Myopia Among Primary and Secondary School Students in Tianjin

Start date: November 1, 2021
Phase:
Study type: Observational

There was a prospective cohort observational study. Forty hyperopic children, 40 myopic children and 120 emmetropia children were randomly selected from grade 1 to grade 3, and were followed up every six months for 3 years. All patients received cycloplegic refraction examination, ocular biological test, binocular visual function test and a questionnaire related to daily eye habits. A multi-level and multi-dimensional data analysis model was constructed to explore the possible factors affecting the occurrence and development of myopia in children.

NCT ID: NCT05604872 Completed - Astigmatism Clinical Trials

Association Between ORA and Residual Refractive Astigmatism After SMILE

Start date: June 1, 2020
Phase:
Study type: Observational

The aim of our study is to analysis and compare the relationship between ORA and postoperative astigmatism in low astigmatism (less than 1D) and moderate to high (1D to 3D) astigmatism patients after SMILE (Small Incision Lenticule Extraction) refractive surgery.

NCT ID: NCT05597397 Recruiting - Myopia Clinical Trials

Effect of Repeated Low-Level Red-Light Therapy on Retinal Function and Structure

Start date: March 1, 2023
Phase: N/A
Study type: Interventional

The purpose of this clinical trial is to evaluate the effect of repeated low-level red-light (RLRL) therapy on the retinal function and structure among myopic teenagers.

NCT ID: NCT05596682 Recruiting - Presbyopia Clinical Trials

Prospective Multicenter Clinical Study on the Visual and Refractive Outcomes and Safety Outcomes Following Implantation of an AddOn Intraocular Lens in Previously Pseudophakic Eyes

Start date: October 17, 2022
Phase:
Study type: Observational

The purpose of this prospective multicenter clinical study is to evaluate the visual and refractive outcomes and safety outcomes following bilateral implantation of trifocal and/or trifocal toric 1stQ AddOn (Medicontur) intraocular lenses (IOLs) to correct residual refractive errors, astigmatism, and presbyopia in previously pseudophakic eyes.

NCT ID: NCT05588362 Not yet recruiting - Myopia Clinical Trials

Access to EyeGlasses for School-aged Children

ATEG
Start date: February 1, 2023
Phase: N/A
Study type: Interventional

Uncorrected refractive error is a leading cause of visual impairment in children and can impact vision, quality of life, and academic performance. Despite Boston Children's Hospital serving patients from a wide range of socioeconomic backgrounds, there are health disparities in access to eyeglasses as a consequence of patients' health insurance. The investigators will examine whether the use of an in-clinic app for 3-D printed glasses reduces disparities in access to eyeglasses for our patients on Medicaid. The intervention will address social determinants of health and improve pediatric health outcomes namely, how and when children having publicly funded health insurance receive eyeglasses. The short-term objectives are (1) to compare the time to receive glasses between publicly funded MassHealth eyeglasses and an in-clinic order of 3D printed glasses (2) to evaluate compliance with glasses wear in these two groups, and (3) to evaluate visual function and quality-of-life outcomes in these two groups. This prospective randomized control study will evaluate barriers to accessing eyeglasses in school-aged children. The investigators will recruit children enrolled in MassHealth and randomize them into two cohorts: (1) the control group will receive MassHealth glasses as per standard of care, through an optical shop of their choosing, or (2) the intervention group will use an app for immediately ordering glasses (paid for by the study) in clinic following their appointment. The investigators will evaluate the time needed to receive eyeglasses, compliance with glasses wear, quality of life, and visual outcomes between the cohorts at one-, three-, and six-month intervals. Through this project, the investigators will not only evaluate, quantify, and bring awareness to disparities in our patient population, but will also look toward finding a solution through the use of a novel application that addresses many of the barriers faced by patients insured through Medicaid.

NCT ID: NCT05583253 Recruiting - Refractive Errors Clinical Trials

Visual Outcome of Vitrectomy After Refractive Surgery

Start date: October 13, 2022
Phase: N/A
Study type: Interventional

Results of retinal detachment surgery may be affected in cases with history of previous intraocular surgery.

NCT ID: NCT05565937 Completed - Clinical trials for Refractive Ametropia

A Study to Evaluate the Safety and Effectiveness of a Contact Lens Cleaning and Disinfecting Solution

Start date: April 12, 2023
Phase: N/A
Study type: Interventional

Approximately 340 participants (680 eyes) will be enrolled in this three-month, two-arm, 1:1 randomized, parallel-group, bilateral, double-masked study at approximately 22 investigative sites in the United States. Participants will be required to wear dispensed study lenses on a daily wear basis for three months with scheduled in-office replacement of study lenses at the 1-Month and 2-Month Follow-Up Visits.

NCT ID: NCT05550740 Not yet recruiting - Eye Diseases Clinical Trials

Repeated Low-Level Red-Light Therapy for Shortening Axial Length

Start date: October 22, 2022
Phase: N/A
Study type: Interventional

The purpose of this clinical trial is to confirm the incidence and magnitude of axial length shortening after RLRL therapy in Chinese high myopia children and teenagers.

NCT ID: NCT05516082 Completed - Ametropia Clinical Trials

Clinical Evaluation of Two Daily Disposable Lenses in Sphere Design

Start date: August 8, 2022
Phase: N/A
Study type: Interventional

This was a single-blind, interventional, prospective, direct refit, bilateral wear, fixed-sequence crossover study.