The Evolutionary Model of Mild-to-moderate Myopia in China

Refractive Error Clinical Trial

Official title:

The Evolutionary Model of Mild-to-moderate Myopia in China

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02667509
• Other study ID #: CCPMOH2016-China2
• Status: Completed
• Phase: N/A
• First received: January 24, 2016
• Last updated: April 12, 2016
• Start date: January 2005
• Est. completion date: October 2015

Study information

• Verified date: April 2016
• Source: Sun Yat-sen University
• Contact: n/a
• Is FDA regulated: No
• Health authority: China: Ministry of Health
• Study type: Observational

Clinical Trial Summary

Myopia has emerged as a major health issue in east Asia, because of its increasingly high prevalence in the past few decades (now 80-90% in school-leavers), and because of the sight-threatening pathologies associated with high myopia, which now aff ects 10-20% of those completing secondary schooling in this part of the world. Similar, but less marked, changes are occurring in other parts of the world. The higher prevalence of myopia in east Asian cities seems to be associated with increasing educational pressures, combined with life-style changes, which have reduced the time children spend outside.

Description:

Myopia has emerged as a major health issue in east Asia, because of its increasingly high prevalence in the past few decades (now 80-90% in school-leavers), and because of the sight-threatening pathologies associated with high myopia, which now aff ects 10-20% of those completing secondary schooling in this part of the world. Similar, but less marked, changes are occurring in other parts of the world. The higher prevalence of myopia in east Asian cities seems to be associated with increasing educational pressures, combined with life-style changes, which have reduced the time children spend outside.

In this trial, the investigators aim to study the evolutionary model of myopia in China, which could provide new insight into the social development and human adaptation.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 852441
• Est. completion date: October 2015
• Est. primary completion date: October 2015
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• Patients complete the examination of Refractive error from 2005 to 2015 year.

Exclusion Criteria:

• Patients could not complete the examination of Refractive error

Study Design

Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

• Refractive Error
• Refractive Errors

Locations

Country	Name	City	State
China	Zhongshan Ophthalmic Center, Sun Yat-sen University	Guangzhou	Guangdong

Sponsors (2)

Lead Sponsor	Collaborator
Sun Yat-sen University	Ministry of Health, China

Country where clinical trial is conducted

China, 

References & Publications (1)

Morgan IG, Ohno-Matsui K, Saw SM. Myopia. Lancet. 2012 May 5;379(9827):1739-48. doi: 10.1016/S0140-6736(12)60272-4. Review. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Refractive error of both eyes measured by autorefractor and subjective measuring		Baseline	No

External Links

•   Home page of Zhongshan Ophthalmic Center