Cervical Vagus Nerve Block Prevents Ocularvagal Reflex

Reflex, Oculocardiac Clinical Trial

Official title: Ultrasound-guided Cervical Vagus Nerve Block Prevents Ocularvagal Reflex in Ophthalmic Surgery

Status Recruiting

Clinical Trial Summary

In ophthalmic surgery, surgical operations such as pulling certain eye tissues or compressing the eyeball often leads to bradycardia, arrhythmia even cardiac arrest, bradypnea, nausea and vomiting and elevated blood sugar level. The condition is called the ocularvagal reflex (OVR). Traditionally, when the bradycardia or arrhythmia happens, the operation has to be suspended, and atropine or isoproterenol is given intravenously to treat the bradycardia. Vagus nerve block may be an effective way to prevent and alleviate this vagal reflex. However it is difficult to perform the nerve block with anatomical landmark (blind) methods. In this study, the investigators used ultrasound-guided right cervical vagus nerve block to reduce the incidence of the OVR. The researchers hypothesized that low concentrations of lidocaine or ropivacaine can block the right cervical vagus nerve and reduce the incidence of intraoperative OVR. Researchers evaluated the changes of heart rate, blood pressure, oxygen saturation, and airway pressure in patients undergoing high-risk OVR surgery.

Clinical Trial Description

n/a

Related Conditions & MeSH terms

• Reflex, Oculocardiac

• NCT number: NCT04950881
• Study type: Interventional
• Source: Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
• Status: Recruiting
• Phase: N/A
• Start date: July 1, 2021
• Completion date: March 31, 2023