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Recurrent Pericarditis clinical trials

View clinical trials related to Recurrent Pericarditis.

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NCT ID: NCT06071156 Recruiting - Clinical trials for Recurrent Pericarditis

Therapy Management in Patients Treated With Anakinra Due to Recurrent Pericarditis

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

To determine the utility of serial cardiac magnetic resonance (CMR) imaging for guidance of therapy management in patients treated with anakinra due to recurrent pericarditis (RP), compared with c-reactive protein (CRP) assay alone.

NCT ID: NCT05494788 Active, not recruiting - Clinical trials for Recurrent Pericarditis

Impact of CardiolRxTM on Recurrent Pericarditis (MAvERIC-Pilot)

Start date: November 30, 2022
Phase: Phase 2
Study type: Interventional

Patients with recurrent pericarditis who are refractory or intolerant to current therapeutic management options or who require long-term administration of corticosteroids to control their disease are particularly challenging to manage. The pathogenesis of pericarditis involves the activation of the inflammasome. CardiolRxTM (a pure cannabidiol [CBD] solution) is known to have anti-inflammatory properties, including modulation of inflammasome signaling. This pilot study is to assess the tolerance and safety of CardiolRxTM during the resolution of pericarditis symptoms, assess improvement in objective measures of disease, and during the extension period, assess the feasibility of weaning concomitant background therapy including corticosteroids while taking CardiolRxTM.

NCT ID: NCT05107934 Not yet recruiting - Clinical trials for Recurrent Pericarditis

Efficacy and Safety of RPH-104 Treatment in Patients With Recurrent Pericarditis

Start date: December 2023
Phase: Phase 2/Phase 3
Study type: Interventional

The primary purpose of this study is the evaluation of the efficacy and safety of RPH-104 treatment in patients with recurrent pericarditis. Pharmacokinetic and pharmacodynamic parameters of RPH-104 multiple doses in this patient population will be assessed as well.

NCT ID: NCT04687358 Recruiting - Clinical trials for Recurrent Pericarditis

REgiStry Of the NAtural History of recurreNt periCarditis in pEdiatric and Adult Patients

RESONANCE
Start date: March 16, 2021
Phase:
Study type: Observational [Patient Registry]

The registry will focus on furthering the understanding of the natural history of recurrent pericarditis (RP), as well as document RP-related clinical, health-related quality of life (HRQoL), and economic burden and will assist the medical community to refine or develop data-driven recommendations for clinical management of RP patients to optimize clinical outcomes. It also aims to generate data in support of the impact of rilonacept on clinical outcomes in a real-world population.

NCT ID: NCT03980522 Completed - Clinical trials for Recurrent Pericarditis

A Pilot Study of KPL-914 in Recurrent Pericarditis

Start date: January 24, 2018
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the preliminary efficacy and safety of KPL-914 treatment in participants with recurrent pericarditis.

NCT ID: NCT03737110 Completed - Clinical trials for Recurrent Pericarditis

Study to Assess the Efficacy and Safety of Rilonacept Treatment in Participants With Recurrent Pericarditis

RHAPSODY
Start date: January 7, 2019
Phase: Phase 3
Study type: Interventional

The primary objective of this study was to assess the efficacy of rilonacept treatment in participants with recurrent pericarditis.