Clinical Trial Details
— Status: Completed
Administrative data
| NCT number |
NCT02746588 |
| Other study ID # |
H-15011157 |
| Secondary ID |
|
| Status |
Completed |
| Phase |
|
| First received |
|
| Last updated |
|
| Start date |
February 1, 2016 |
| Est. completion date |
January 1, 2019 |
Study information
| Verified date |
March 2022 |
| Source |
Hvidovre University Hospital |
| Contact |
n/a |
| Is FDA regulated |
No |
| Health authority |
|
| Study type |
Observational
|
Clinical Trial Summary
To be diagnosed with recurrent miscarriages, a couple might have a child, however experiences
three or more miscarriages, primarily this happens during the first trimester.
These miscarriages often needs medical evacuation or a D & C. Surgery or retained tissue
increases the risk of complications as infection and/or adhesions, known as asherman
syndrome, which may result in subfertility.
Recently chronic infection in the endometrium has been proposed to contribute to the
condition, as protocols including treatment with antibiotics have led to birth at term for
some of these women.
Using the very minimal invasive office hysteroscopy, the investigators aim to describe the
uterine cavity in patients diagnosed with recurrent miscarriages regarding both abnormalities
in the endometrium and chromic infection.
Description:
The Unit for Recurrent Pregnancy-loss at Rigshospitalet treats about 300 of couples with
recurrent miscarriages a year. Together with the current examination program, the
investigators plan to describe the uterine cavity according to abnormalities as septa,
adhesions and further the condition for the endometrium regarding infection and hormone
receptors. This description will include descriptive office hysteroscopy with biopsies for
histologic - and immunohistochemically examinations.
