Effect of Prednisolone Treatment on Uterine Natural Killer Cells

Status Recruiting

Clinical Trial Summary

This study aims to investigate the role of uNK cells and the association with prednisolone.

Clinical Trial Description

Glucocorticoids prednisolone is considered as a potential therapy in women with recurrent miscarriage. However, the evidence for treatment with prednisolone is still inconclusive and the relevant mechanism merits further investigations. The participants will be invited to take prednisolone oral 10 mg/day and attend our outpaitent clinic to be performed endometrial biopsy. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03902912
Study type	Interventional
Source	Chinese University of Hong Kong
Contact	Stacey Wong, BSc
Phone	85235051764
Email	staceywong@cuhk.edu.hk
Status	Recruiting
Phase	Phase 3
Start date	July 30, 2019
Completion date	April 30, 2028

View Details

See also
Status	Clinical Trial	Phase
Active, not recruiting	`NCT01419392` - Role of Sildenafil Citrate in Patients With Unexplained Recurrent Miscarriages	Phase 4
Completed	`NCT00193674` - Habitual Abortion Study: Oral Dydrogesterone Treatment During Pregnancy in Women With Recurrent Miscarriage	Phase 3
Completed	`NCT06001060` - Distinct Alterations in Gut Microbiota Composition Among Women of Reproductive Age With Elevated Homocysteine Levels.
Recruiting	`NCT05034250` - Iron Status in Female Infertility and Recurrent Miscarriage
Completed	`NCT02681627` - Sim (Scratch in Miscarriage) Study	N/A
Recruiting	`NCT02303171` - Use of Warfarin After the First Trimester in Pregnant Women With APS	Phase 4
Completed	`NCT02305420` - EmbryoGen/ Blastgen for Couples With Implantation Problems or Previous Miscarriage	Phase 4
Recruiting	`NCT05824897` - The Cohort Study of the Correlation Between Serum 25(OH)D Level and Pregnancy Outcome
Completed	`NCT03023137` - Walking and Dietary Modification for Recurrent Early Miscarriages	N/A
Not yet recruiting	`NCT03132779` - Intralipid Related Effect on NKcells in Patients With Unexplained Recurrent Spontaneous Abortion	Phase 1
Completed	`NCT02184741` - A Study of the Efficacy and Safety of GB-0998 in Patients With Unexplained Recurrent Miscarriage	Phase 3
Active, not recruiting	`NCT02156063` - A Multi-center, Placebo-controlled Study to Evaluate NT100 in Pregnant Women With a History of Unexplained Recurrent Pregnancy Loss (RPL)	Phase 2
Not yet recruiting	`NCT03209063` - The Role of Prothrombin Gene and Methylenetetrahydrofolate Reductase(MTHFR) Gene Polymorphisms as Risk Factors for Recurrent Miscarriage
Completed	`NCT03970954` - Low-dose Interleukin-2 in Women With Unexplained Miscarriages	Phase 1/Phase 2
Not yet recruiting	`NCT06249230` - The Analysis of Risk Factors for Recurrent Pregnancy Loss and Prediction of Pregnancy Loss Risk
Recruiting	`NCT05725512` - Prednisolone Administration in Patients With Unexplained REcurrent MIscarriages	Phase 4
Recruiting	`NCT05267678` - Nutritional Deficiency and Recurrent Miscarriage
Completed	`NCT02694367` - Expression of EPK in Recurrent Miscarriage	N/A
Completed	`NCT02504281` - Study on the Association Between SXCI and RM and the Possible Genetic Mechanism
Completed	`NCT01608347` - Low Molecular Weight Heparin in Recurrent Miscarriage With Negative Antiphospholipid Antibodies	Phase 4