Recurrent Head and Neck Cancer Clinical Trial
Official title:
A Pilot Study of Cetuximab and the Hedgehog Inhibitor IPI-926 in Recurrent Head and Neck Cancer: a Rational Anti-Cancer Stem Cell Combination.
This study will evaluate the clinical activity of the combination of ipilimumab (IPI) -926 in combination with cetuximab in patients with advanced head and neck cancer.
The purpose of this study is to determine the dose-limiting toxicities and the recommended dose for phase 2 evaluation of the combination of IPI-926 and cetuximab in patients with advanced head and neck cancer. ;
Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Not yet recruiting |
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N/A | |
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Phase 2 | |
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Phase 2 | |
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Phase 2 | |
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Phase 1/Phase 2 | |
| Terminated |
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Phase 2/Phase 3 | |
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Phase 2 | |
| Completed |
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Phase 3 | |
| Completed |
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Phase 1/Phase 2 | |
| Completed |
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A Study of Mitoxantrone Hydrochloride Liposome Injection in the Treatment of Recurrent/Metastatic Head and Neck Cancers
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Phase 1 | |
| Recruiting |
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|
Phase 2 | |
| Active, not recruiting |
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Phase 2 | |
| Recruiting |
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Phase 2 | |
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| Recruiting |
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Phase 1/Phase 2 | |
| Terminated |
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Phase 2 | |
| Terminated |
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Phase 3 | |
| Terminated |
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Phase 2 | |
| Completed |
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Phase 2 |