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Clinical Trial Summary

The purpose of this research study is to test the safety of Niraparib and dostarlimab as a combination treatment and see what effects (good and bad) this combination treatment has on patients with recurrent or progressive cervix cancer.


Clinical Trial Description

Patients will have tests and exams to see if they are eligible for the clinical trial. If found eligible, the patient will receive treatment with Niraparib daily and dostarlimab by vein every three weeks for 4 cycles then every six weeks. Patients will receive the study treatment as long as there is evidence that the tumor is not growing or spreading and they are not having any unacceptable, bad side effects. Patients will be monitored during treatment with tests and exams and after treatment completion for up to 5 years. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04068753
Study type Interventional
Source University of Oklahoma
Contact Lead Gyn Onc, Nurse
Phone 1-405 271-8777
Email SCC-IIT-Office@ouhsc.edu
Status Recruiting
Phase Phase 2
Start date February 26, 2020
Completion date July 2027