Recurrence of Acute Alcoholic Pancreatitis

Recurrent Acute Pancreatitis Clinical Trial

Official title:

Recurrence of Acute Alcoholic Pancreatitis

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00523874
• Other study ID #: R00126
• Status: Completed
• Phase: N/A
• First received: August 31, 2007
• Last updated: August 31, 2007
• Start date: January 2001
• Est. completion date: May 2007

Study information

• Verified date: January 2001
• Source: University of Tampere
• Contact: n/a
• Is FDA regulated: No
• Health authority: Finland: Ethical commettee of Federatio of Municipalities in the Hospital District of Pirkanmaa and National Authority for Medicolegal Affairs
• Study type: Observational

Clinical Trial Summary

Previously our retrospective study showed that almost half of the patients with acute alcoholic pancreatitis had a recurrent attack in the long-term, mild pancreatitis and young age being risk factors for recurrence. The aim of this prospective follow-up study was aimed to find out the risk factors in detail.

Description:

Patients admitted to Tampere University Hospital for first acute alcoholic pancreatitis were included. The diagnostic criteria for acute pancreatitis were epigastric pain, serum amylase > 3 x upper normal range, elevated serum CRP and signs of acute pancreatitis in imaging. Other etiologies were excluded. Alcohol consumption and dependency were detected. Serum and fecal markers of the endocrine and exocrine function and secretin stimulated MRCP were studied. The patients were followed median 38 (25 - 61) months for the recurrences and had a follow up visit at two years to investigate trends in the alcohol consumption.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 120
• Est. completion date: May 2007
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Patients who survived their first acute alcoholic pancreatitis. The diagnostic criteria for acute pancreatitis were epigastric pain, serum amylase > 3 x upper normal range, elevated serum CRP and signs of acute pancreatitis in imaging. Other etiologies were excluded.

• High alcohol consumption was detected

Study Design

Observational Model: Defined Population, Primary Purpose: Screening, Time Perspective: Longitudinal

Related Conditions & MeSH terms

• Pancreatitis
• Recurrent Acute Pancreatitis

Locations

Country	Name	City	State
Finland	Tampere University Hospital	Tampere

Sponsors (1)

Lead Sponsor	Collaborator
University of Tampere

Country where clinical trial is conducted

Finland,