Role of Low Inferior Mesenteric Artery Ligation During Laparoscopic Surgery for Rectosigmoid Cancer

Rectosigmoid Adenocarcinoma Clinical Trial

Official title:

Evaluation of the Role of Low Inferior Mesenteric Artery Ligation During Laparoscopic Surgery for Rectosigmoid Tumors

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03557528
• Other study ID #: 14ur2018
• Status: Completed
• Start date: January 1, 2014
• Est. completion date: April 30, 2017

Study information

• Verified date: June 2018
• Source: University of Roma La Sapienza
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

During sigmoid or rectal cancer surgery, dissection of lymphnodes at the origin of inferior mesenteric artery is mandatory. Nevertheless, ligation of the origin of IMA should compromise blood supply to left colon and affect anastomosis. The aim of this retrospective evaluation is to compare high and low IMA ligation with preservation of LCA, with or without skeletonization of the origin of IMA in laparoscopic colorectal resection.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 120
• Est. completion date: April 30, 2017
• Est. primary completion date: December 31, 2016
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• stage I-III carcinoma

Exclusion Criteria:

• stage IV

• Urgent resection

• conversion to open surgery

Related Conditions & MeSH terms

• Adenocarcinoma
• Rectosigmoid Adenocarcinoma

Intervention

Procedure:
• Laparoscopic colorectal resection
Gruop 1: laparoscopic rectosigmoid resection with standard ligation of mesenteric artery at its origin Group 2: Laparoscopic rectosigmoid resection with low ligation of inferior mesenteric artery and its skeletonization with en bloc removal of all lymph nodes

Locations

Country	Name	City	State
Italy	Policlinico Umberto I	Roma

Sponsors (1)

Lead Sponsor	Collaborator
University of Roma La Sapienza

Country where clinical trial is conducted

Italy, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	effectivenes of lymphnode dissection	number of dissected lymphnodes	3 years
Secondary	complication	incidence of anasthomotic leaks	3 years