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Rectal Prolapse clinical trials

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NCT ID: NCT06353230 Completed - Rectal Prolapse Clinical Trials

Comparison of Sclerotherapy Agents Used for Rectal Prolapse Treatment in Children

Prolapse
Start date: October 15, 2019
Phase: N/A
Study type: Interventional

Introduction Patients with rectal prolapse are treated with injection sclerotherapy, which is the most often used first-line surgical technique. Injection sclerotherapy has a success rate of 90-100% in youngsters, according to certain studies. Objective To compare the outcome of injection sclerotherapy using 5% Phenol in almond oil, 15% hypertonic saline and 50% dextrose water in the treatment of rectal prolapse in children.

NCT ID: NCT06174584 Completed - Rectal Prolapse Clinical Trials

Comparison of Cow Milk and 15% Hypertonic Saline in the Treatment of Rectal Prolapse in Children

Start date: February 1, 2021
Phase: Early Phase 1
Study type: Interventional

To see the outcome of results of Cow Milk & Hypertonic Saline in the treatment of Rectal Prolapse in Children

NCT ID: NCT05915936 Completed - Rectal Prolapse Clinical Trials

LVMR Versus PSR for External FTRPin Elderly Patients

Start date: April 1, 2012
Phase:
Study type: Observational

In frail patients with external full-thickness rectal prolapse (FTRP), the exact postoperative recurrence and functional result outcomes difference between Laparoscopic ventral mesh rectopexy (LVMR) and perineal stapler resection (PSR) have not been investigated, leading to ineffective treatment. Objectives: Evaluating the efficacy of PSR versus LVMR for treating external FTRP in the elderly. Design: This was a retrospective study that involved multiple centers. Settings: This study was conducted in the colorectal surgical units of our Universities' Hospitals Patients: 330 elderly patients divided into LVMR group (250), and PSR (80) between April 2012 and April 2019. Before and after surgery, patients were evaluated using the Wexner Incontinence Scale, the Altomare Constipation Scale, and the patient's satisfaction. Main outcomes measurement: The primary outcome was the recurrence rate and risk factors of FTRP. Secondary outcomes were postoperative incontinence and constipation and patients' satisfaction.

NCT ID: NCT05254860 Completed - Rectal Prolapse Clinical Trials

Continuous Locked Non-barbed Suture for Mesh Fixation During Laparoscopic Ventral Rectopexy for Severe Rectal Prolapse

Start date: November 2016
Phase: N/A
Study type: Interventional

This prospective randomized pilot study is aimed to verify if the operative time of a standard laparoscopic ventral rectopexy for the treatment of severe rectal prolapse could be further reduced using a continuous locked suture vs. conventional single 6-points suture for mesh fixation.

NCT ID: NCT04892108 Completed - Surgery Clinical Trials

Rectal Prolapse With ODS. STARR vs LVR.

Start date: January 1, 2017
Phase: N/A
Study type: Interventional

The objective of the study will be to evaluate the clinical and functional outcome of patients with obstructed defecation sndrome (ODS) associated to internal rectal prolapse, treated with transanal prolassectomy (STARR) surgery compared to those treated with laparoscopic ventral rectopexy (LVR).

NCT ID: NCT04627610 Completed - Rectal Prolapse Clinical Trials

Recurrence of Dyschezia in Rectal Prolapse, Rectocele and Elytrocele

PEXITY
Start date: March 9, 2022
Phase:
Study type: Observational

Prolapse of the rectum is a pathology that preferentially affects older women with a significant impact on quality of life. A very large number of therapeutic approaches can be proposed (functional treatment, surgical techniques by perineal approach and surgical techniques by anterior approach). D'Hoore and Pennix described Ventral Rectopexy with prosthetic reinforcement which is accepted as a standard of treatment in much of Europe for externalized prolapse but remains maligned in much of the world. Due to the relatively recent appearance of this technique and the great variability in the management methods, the long-term results of Ventral Rectopexy have been little studied. This surgical technique is the preferred approach offered at CHU Grenoble Alpes. Pr Faucheron have internationally recognized experience in surgical grip with a very high patient volume in recent years.

NCT ID: NCT04184310 Completed - Rectal Prolapse Clinical Trials

Modified Perineal Linear Stapler Resection for External Rectal Prolapse: a Novel Approach

Start date: December 5, 2016
Phase: N/A
Study type: Interventional

from December 2016 to July 2019, 36 elderly co-morbid patients with rectal prolapse were involved in this study which is performed in the GIT surgery unit of Zagazig University Hospital. the investigators used a modified linear stapler resection technique for the rectal prolapse. Postoperative follow up was done for one year to evaluate functional outcome, operative time, hospital stay and complications

NCT ID: NCT04130555 Completed - Rectal Prolapse Clinical Trials

Safety and Performance Evaluation of a Biological Matrix Used for Rectal Prolapse Repair by Ventral Rectopexy

Start date: December 11, 2019
Phase:
Study type: Observational

The general objective of the study is to confirm the medium/long-term safety and clinical performance of the CELLIS Rectopexy membrane used in rectal prolapse repair by ventral rectopexy and to identify emerging risks in comparison to the clinical data related to other types of fixation material. The present study will be a prospective multicentric non-randomized and non-controlled trial involving 55 patients followed for 24 months. The study will be conducted in France in 3 investigational centres.

NCT ID: NCT04117633 Completed - Rectal Prolapse Clinical Trials

Laparoscopic Suture Versus Mesh Rectopexy for the Treatment of Persistent Complete Rectal Prolapse in Children

Start date: February 1, 2010
Phase: N/A
Study type: Interventional

Purpose: to compare Laparoscopic mesh rectopexy with laparoscopic suture rectopexy The operative time, recurrence rate, post-operative constipation, and effect on fecal incontinence, were reported and evaluated for each group Results:

NCT ID: NCT03643393 Completed - Rectal Prolapse Clinical Trials

Report 2 Cases of Massive Incarceration Necrosis Rectal Prolapse Are Successfully Treated With Altemeier's Procedure

Start date: May 1, 2015
Phase: N/A
Study type: Interventional

Incarceration and necrosis of rectal prolapse is rare and often requires urgent management. Perineal rectosigmoidectomy (Altemeir procedure) is a reasonable technique for this condition. The need for a diverting stoma depends on the patient's condition and the experience and judgement of the surgeon. A literature review was performed to determine optimal management of incarcerated and necrotic rectal prolapse, and to determine the indication for fecal diversion.