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Rectal Fistula clinical trials

View clinical trials related to Rectal Fistula.

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NCT ID: NCT04357210 Completed - Anorectal Fistula Clinical Trials

Anal Sphincter Reconstruction After High Recurrent Anorectal Fistula Excision

Start date: January 1, 2016
Phase:
Study type: Observational

A retrospective analysis of patients treated for recurrent posterior anorectal fistula, who previously had undergone radical excision of fistula-in-ano, was performed. Three types of surgical reconstruction were compared: fistulectomy with primary sphincteroplasty, muco-muscular advancement flap and full-thickness low rectum posterior semicircular mobilization.

NCT ID: NCT04351074 Completed - Clinical trials for Transsphincteric Anal Fistula

Ligation of Intersphincteric Track (LIFT) Versus Fistulectomy in Trans-sphincteric Anal Ffistula.

professor
Start date: March 1, 2018
Phase: N/A
Study type: Interventional

78 patients with transsphincteric fistula allocated into two groups group A underwent LIFT group B u nderwent fistulectomy , comparison between the outcome og both procedures

NCT ID: NCT04326907 Completed - Anal Fistula Clinical Trials

Treatment of Complex Anal Fistulas Using Centrifuged Adipose Tissue Containing Progenitor Cells

CAT
Start date: May 1, 2016
Phase: N/A
Study type: Interventional

In the treatment of complex anal fistulas transplant of freshly collected autologous adipose tissue mechanically fragmented or centrifuged adipose tissue (CAT) might be an alternative to in vitro expanded autologous or allogeneic adipose-derived stem cells, showing remarkable efficacy in diverse therapeutic indications. The aim of our study is to evaluate randomly the efficacy and safety of the use of CAT in the healing process of complex anal fistulas, except for Crohn's disease (CD) related fistulas.

NCT ID: NCT04319861 Completed - Recurrence Clinical Trials

Anal Fistula Plug, a Retrospective Study

Start date: August 1, 2008
Phase: N/A
Study type: Interventional

In this study, we retrospectively reviewed clinical data of patients who were treated with an anal fistula plug for trans-sphincteric anal fistulas, and evaluated the long-term therapeutic effect of an anal fistula plug and the risk factors impacting anal fistula healing. In addition, we assessed the effects of post-operative changes on anal function, as well as the risk factors affecting anal function.

NCT ID: NCT04215718 Completed - Fistula in Ano Clinical Trials

Fistulotomy With Marsupialization Versus Fistulectomy With Wound Sutures in Simple Anal Fistula

Start date: April 1, 2017
Phase: N/A
Study type: Interventional

comparison between fistulectomy wound closure and fistulotomw wound marsupialization in treatment of simple anal fistula

NCT ID: NCT04155905 Completed - Anal Fistula Clinical Trials

Marsupialization of Anal Fistulotomy Wound Accelerates Healing and Decreases Post Operative Pain

Start date: May 1, 2018
Phase: N/A
Study type: Interventional

comparison between to groups of patients with simple anal fistula one group underwent sistulotomy the other underwent fistulotomy and marsupialization of the wound edges , the investigator tested the incidence of postoperative complications , time of wound healing , operative time

NCT ID: NCT04075825 Completed - Crohn's Disease Clinical Trials

Long-term Follow-up Study With Darvadstrocel in the Treatment of Complex Perianal Fistula

Start date: November 4, 2019
Phase: Phase 3
Study type: Interventional

The main aim is to follow-up on long term side effect and symptom improvement of Darvadstrocel in the treatment of complex perianal fistula in adults. Participants will not receive any drug in this study.

NCT ID: NCT04069728 Completed - Fistula in Ano Clinical Trials

The Impact of 3D Anal Fistula Models on Patient Understanding and Decision Making

3DAF
Start date: November 2, 2020
Phase: N/A
Study type: Interventional

An anal fistula is an abnormal communication between the luminal surface of the anorectal canal and the perianal skin. Fistulas can vary in their complexity and can be challenging to treat, due to the anatomical relation to the anal sphincter complex that controls continence. In addition, fistulas can display complex features such as branches, cavities and horseshoes; where the tract travels radially around the anal canal. All these features have a role in determining the most appropriate surgical treatment option, and are key to understanding the surgical decision-making process. This study will determine patient understanding of fistula anatomy, their perception of their own understanding, their rating of how good their clinician's explanation is and how this impacts the decision-making process using standard explanation with 2D images, versus a 3D printed model of a fistula.

NCT ID: NCT03983174 Completed - Anal Cancer Clinical Trials

Drainage Seton With Flap Versus EAS Preserving Seton in Treatment of Transsphincteric Anal Fistula

Start date: January 1, 2017
Phase: N/A
Study type: Interventional

Patients with high trans-sphincteric anal fistula will be randomized to one of two equal group: group 1 will have drainage seton with mucosal advancement flap and group 2 will undergo external anal sphincter sparing seton

NCT ID: NCT03981939 Completed - Clinical trials for Inflammatory Bowel Disease

Perianal Fistula (PAF) Validation and Burden of Illness Study

Start date: July 2, 2019
Phase:
Study type: Observational

The purpose of this study is to gain a better understanding of the disease burden and unmet need of perianal fistulas within Crohn's disease (CD) in Ontario.