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NCT05381324 Clinical Trial

Fistula-associated Anal Adenocarcinoma

Rectal Cancer Clinical Trial

Official title:
Fistula-associated Anal Adenocarcinoma - a Twenty Years' Single-center Experience.

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT05381324
Other study ID # 1258
Secondary ID
Status Completed
Phase
First received
Last updated
Start date January 1, 1999
Est. completion date May 1, 2022

Study information
Verified date May 2022
Source Medical University of Vienna
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The fistula-associated anal adenocarcinoma is rare in patients suffering from anal fistulas. There is only little data available for this patient collective making characterization and management of this disease difficult. Late diagnosis and advanced tumor stage at diagnosis result in poor clinical outcome. It is the purpose of this study to evaluate patients clinically diagnosed with a FAAC and to further perform a histopathological characterization of the available tumor specimen.

Description:

All patients receiving surgery for an anal fistula in the years 1999 to 2019 at a tertiary university referral hospital were included in the analysis. A retrospective review of patients' charts was performed. Patients suffering from FAAC were eligible for histopathological analysis including immunohistochemistry and molecular profiling.

Recruitment information / eligibility
Status Completed
Enrollment 1004
Est. completion date May 1, 2022
Est. primary completion date December 31, 2019
Accepts healthy volunteers No
Gender All
Age group N/A and older
Eligibility Inclusion Criteria: - anal fistula Exclusion Criteria: - previous cancer of the anal canal

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Medical University of Vienna

Outcome
Type Measure Description Time frame Safety issue
Primary fistula-associated anal adenocarcinoma (FAAC) include and analyze all patients suffering from FAAC 1999-2019
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