Recovery Clinical Trial
Official title:
Comparison of the Effect of Continuous Infusion and Bolus Doses of Rocuronium During Anesthesia for Lumbal Discectomy on Muscle Strength and Quality of Patient Recovery
The continuous infusion of rocuronium during general anesthesia for a lumbar discectomy enables better muscle strength recovery, and a better quality of patient recovery as measured by questionnaire.
Rocuronium is a non-depolarising neuromuscular blocking agent that can be administered in
bolus doses or via continuous infusion during general anesthesia. Due to the specificity of
the knee-chest position in a lumbar discectomy, many complications during anesthesia and
surgery are possible. Therefore an effective and balanced intraoperative neuromuscular block
is needed.
Studies so far have not included a comparison on muscle strength and quality of patient
recovery of the effect of continuous infusion and bolus doses of rocuronium during anesthesia
for lumbar discectomy.
The hypothesis of this research was that the continuous infusion of rocuronium during general
anesthesia for a lumbar discectomy enables better muscle strength recovery, and a better
quality of patient recovery as measured by questionnaire.
The aim was to compare the influence of the continuous infusion and bolus doses of rocuronium
on patient recovery. Therefore the investigators assessed how continuous infusion and bolus
doses of rocuronium affect the recovery of muscle strength as measured by a hand-grip
dynamometer. The quality of patient recovery was assessed by standardised questionnaire
(Qor-40 - Quality of recovery questionnaire).
The aim was also to evaluate the applicability of the Croatian version of Qor-40
questionnaire in clinical practice.
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