Reconstruction Breast Surgery Clinical Trial
Official title:
Thoracic Paravertebral Block Versus Pectoral Nerves Block (Modified PECS) Block in Breast Surgery
Purpose to compare paravertebral thoracic block (PVB) and pectorals nerves block as
analgesic option for major breast surgery.
102 patients undergoing reconstruction breast surgery will be randomized into two groups:
Group PVB (n=51) will receive US guided paravertebral thoracic block (between T2-T6)
performed with 30ml of 0.25% levobupivacaine before general anesthesia (TCI-TIVA) induction.
Morphine patient control analgesia (PCA) with loading dose i.v. titrated by the PACU nurse
if pain > 5/10 at rest Group PECS (n=51) will receive US guided pectorals nerves block
performed with 30ml of 0.25% levobupivacaine before general anesthesia (TCI-TIVA) induction.
Morphine PCA with loading dose i.v. titrated by the post-anesthesia care unit (PACU) nurse
if pain > 5/10 at rest
Primary Outcome Measures:
Morphine consumption (mg) (Time Frame: 24 hours) in two Groups
Secondary Outcome Measures:
Pain at rest and during movement quantified as Numerical Rating Scores (0-10) during the
first 24 hours postoperatively.
Eventual side effects such as nausea/vomiting. Time necessary to perform the procedure. Pain
during procedure execution quantified as Numerical Rating Scores (0-10) Hypnotic and opioids
intraoperative consumption to ensure general anesthesia with Bispectral Index between 40 and
60.
n/a