Clinical Trials Logo

Clinical Trial Summary

The main objective of the study is to determine if implication of epoxy-eicosatriénoïc acids (EETs) and NO during cutaneous post-occlusive hyperemia differs between patients with Raynaud phenomena and healthy volunteers, by studying hyperaemic postocclusive response after microinjection of fluconazole and L-NMMA at the dorsal side of the fingers.


Clinical Trial Description

The main objective of the study is to determine if implication of epoxy-eicosatriénoïques acids (EETs) and NO during cutaneous post-occlusive hyperemia differs between patients with Raynaud phenomena and healthy volunteers, by studying hyperaemic postocclusive response after microinjection of fluconazole and L-NMMA at the dorsal side of the fingers.

Healthy controls and patients will undergo 3 visits ;


Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Basic Science


Related Conditions & MeSH terms


NCT number NCT02183779
Study type Interventional
Source University Hospital, Grenoble
Contact Jean-Luc CRACOWSKI, MD-PhD
Phone +33476769260
Email JLCracowski@chu-grenoble.fr
Status Recruiting
Phase N/A
Start date June 2014
Completion date June 2017

See also
  Status Clinical Trial Phase
Not yet recruiting NCT02735070 - Study Comparing Coristina® D to Resfenol® in the Symptomatic Treatment of Common Cold Phase 3
Completed NCT05247333 - Implementation of a Minor Ailment Service in Community Pharmacy Practice N/A
Not yet recruiting NCT05118672 - Phase 3 Clinical Trial to Evaluate Paracetamol /Fexofenadine /Phenylephrine in Flu and Cold Treatment Phase 3
Recruiting NCT06158659 - Improved Immunology Outcomes Associated With Lactoferrin Fortified With HMO in Infant Formula N/A
Active, not recruiting NCT05190432 - Taxifolin/Ergothioneine and Immune Biomarkers in Healthy Volunteers (TaxEr) N/A
Not yet recruiting NCT03089138 - Efficacy and Safety of Regan Tangjiang for Treating the Common Cold With Wind-heat Syndrome Phase 2
Completed NCT00289237 - Lifestyle Intervention in a General Population for Prevention of Ischaemic Heart Disease N/A
Recruiting NCT05728918 - Effectiveness of Antrodia Cinnamomea Mycelia on Improving Immune Response in Subhealth People N/A
Completed NCT05920915 - The Effect of the Cold Application on Venous Cannulation Pain N/A
Recruiting NCT05454826 - Investigation of the Effect of Cold Application in Migraine N/A
Recruiting NCT04277494 - The Acute Effect of Cold Spray Application on the Mechanical Properties of the Quadriceps Muscle in Athletes N/A
Completed NCT01533220 - Efficacy of Nasal Naphazoline Hydrocloride + Pheniramine Maleate + Panthenol Compared With Naphazoline Hydrocloride in the Symptomatic Control of Nasal Congestion and Nasopharyngeal Phase 3
Not yet recruiting NCT04277481 - The Acute Effect of Cold Pack Therapy Applied on Healthy People for Different Periods
Completed NCT03769012 - Ability of Beta-glucan Supplementation to Augment Immune Function N/A
Suspended NCT02904304 - Desloratadine,Phenylephrine Hcl,Ibuprofen Compared to Placebo in Treatment of Symptoms Associated With Common Cold/Flu Phase 3
Completed NCT02238210 - Safety Trial of Atrovent® in Pediatric Patients With Rhinorrhea Associated With a Common Cold or Allergy Phase 4
Recruiting NCT05435144 - Elderberry for Immune Support N/A
Completed NCT02847663 - The Effect of Whole Body Cryotherapy on Recovery and Performance: a Randomized Controlled Trial N/A
Recruiting NCT02457533 - Case Management - Active Telephone Support to Patients With COLD N/A
Not yet recruiting NCT05317156 - The Effect of Cold Vapor on Intubation-Related Symptoms and Comfort in the Early Postoperative Period N/A