Classic and Modified Rapid Sequence Induction for Prevention of Gastric Content Regurgitation

Rapid Sequence Induction Clinical Trial

Official title:
Comparison of Classic and Modified Rapid Sequence Induction on Prevention of Perioperative Gastric Content Regurgitation in Emergency Surgery Under General Anesthesia

Status Completed

Clinical Trial Summary

Induction of anesthesia induces a loss of protective upper airway reflexes and is associated with gastric content regurgitation. Emergency surgery bears a higher risk of gastric content regurgitation because of full stomach, delayed gastric emptying, intestinal obstruction, stroke or other factors. Rapid sequence induction (RSI) of anesthesia was recommended to minimize the risk of regurgitation and aspiration. Classic RSI scheme mainly includes the use of short-acting sedatives and muscle relaxant, together with a manual pressure to the cricoid cartilage (Sellick maneuver) which aims at compressing the esophagus to avoid regurgitation. Though widely recommended, the scheme has been controversial for years. Our department modified the scheme and put it into use in day shift emergency surgery since March 1, 2018. This retrospective analysis is aimed at comparing the effect of classic and modified rapid sequence induction in prevention of gastric content regurgitation in emergency surgery under general anesthesia.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Rapid Sequence Induction

Clinical Trial Details

NCT number	NCT04312425
Study type	Observational
Source	The First Affiliated Hospital with Nanjing Medical University
Contact
Status	Completed
Phase
Start date	March 5, 2020
Completion date	March 15, 2020

View Details

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