Clinical Trial Details
— Status: Not yet recruiting
Administrative data
NCT number |
NCT06469346 |
Other study ID # |
MGTFNG-2024 |
Secondary ID |
|
Status |
Not yet recruiting |
Phase |
N/A
|
First received |
|
Last updated |
|
Start date |
August 5, 2024 |
Est. completion date |
March 28, 2025 |
Study information
Verified date |
June 2024 |
Source |
Universidad de La Frontera |
Contact |
Nicolás A Garrido-Muñoz |
Phone |
+56944276072 |
Email |
klgo.nicolasgarrido[@]gmail.com |
Is FDA regulated |
No |
Health authority |
|
Study type |
Interventional
|
Clinical Trial Summary
Background: Muscle flexibility is a fundamental physical quality for body development, daily
life and sports activities, and also for maintaining muscle quality during aging. Limited
flexibility leads to an increased prevalence of musculoskeletal injury in general population
and longer return to sports activities.
Among the existent strategies to increase muscle flexibility in sports training and physical
rehabilitation, static stretching is commonly used by health and physical activity
professionals. Its effectiveness in increasing flexibility has been widely demonstrated;
however its effects on muscle strength and power remains controversial.
Therefore, eccentric resistance exercise has been proposed as an effective intervention for
increasing muscle flexibility through structural changes on muscle architecture (pennation
angle and fascicle length) with the additional benefit of resistance training on muscle
strength and power. Nonetheless, its unknown if the increase in muscle flexibility through
eccentric resistance exercise could be similar to what has been previously demonstrated with
static stretching.
Description:
Hypothesis: The increase in hamstring flexibility after 6 weeks of eccentric resistance
training in young males would be similar compared to 6 weeks static stretching training in
the same population.
Goals: The primary aim of the study is to compare the effectiveness of 6 weeks eccentric
resistance training vs 6 weeks static stretching training on hamstring flexibility in young
males.
Specific Goals: Determine the effect of 6 weeks excentric exercise training and 6 weeks
static stretching training on unilateral maximal isometric voluntary strength between both
groups
To compare the effect of 6 weeks excentric exercise training and 6 weeks static stretching
training in structural changes on muscle architecture (pennation angle, fascicle length and
muscle thickness).
Methodology:
Study design: Forty two young males between 18 and 35 years will be divided into three
groups: hamstring eccentric resistance training group (EEG, n=14), hamstring static
stretching group (SSG, n=14) and control group (CG, n=14). Volunteers of eccentric resistance
training group will be subjected to 6 weeks of Nordic hamstring exercise (3x/wk), while
volunteers of static stretching group will be subjected to 6 weeks of hamstring passive
static stretching (3x/wk). Control group will not attend any type of intervention. Before and
after 6 weeks of training, Knee Extension Angle and Sit and Reach test will be performed for
measuring hamstring flexibility. Unilateral Hamstring Isometric Maximal Voluntary Strength
will be determined by load cell force transducer, and pennation angle, fascicle length and
muscle thickness of Long Head Biceps Femoris will be conducted through muscle ultrasonography
Study parameters/endpoint:
The main study endpoint is the increase in hamstring flexibility assessed with Knee Extension
Angle and Sit and Reach Test.
Secondary endpoints include Unilateral Hamstring Isometric Maximal Voluntary Strength (IMVS)
and Architectural changes in Long Head Biceps Femoris muscle.
Other parameters include age, body weight, body height, body mass index (BMI), level of
physical activity.
Expected results: With the proposed project, the investigators expect that eccentric exercise
training will increase hamstring muscle flexibility at similar level compared with static
stretching training. The findings will define the potential of eccentric exercise training on
muscle flexibility in healthy participants. These results could expand the benefits of this
type of exercise training focused on being included in populations with limited mobility such
as elderly and injured populations